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[高血压合并性功能障碍的中医认识与治疗策略]

[TCM understanding and treatment strategy of hypertension complicated with sexual dysfunction].

作者信息

Jin Zi-Xuan, Luo Fu-Kun, Yu Yue, Liu Wei, Wang Peng-Qian, Xiong Xing-Jiang

机构信息

Guang'anmen Hospital, China Academy of Chinese Medical Sciences Beijing 100053, China.

Beijing Hospital of Traditional Chinese Medicine, Capital Medical University Beijing 100010, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2023 Apr;48(7):1982-1988. doi: 10.19540/j.cnki.cjcmm.20230202.501.

Abstract

Hypertension and its target organ damage have become a major public health problem. Sexual dysfunction is a new problem in the treatment of modern hypertension. Modern pathophysiological studies have shown that hypertension can lead to sexual dysfunction. In addition, three major hypotensive drugs represented by diuretics can also lead to sexual dysfunction. In traditional Chinese medicine(TCM), hypertension belongs to "vertigo" "headache" "head wind", etc. In the past, the understanding of the TCM pathogenesis of hypertension was mainly from the perspectives of "liver wind" and "Yang hyperactivity". However, based on the in-depth research on ancient and modern literature and medical records and many years of clinical practice, it has been identified that kidney deficiency was the key pathogenesis. Hypertension complicated with sexual dysfunction belongs to the category of kidney deficiency syndrome in TCM, especially the deficiency of kidney Yin. Previous studies by other research groups showed that Yin-enriching and kidney-tonifying method could effectively reduce blood pressure, improve sexual dysfunction, reverse risk factors, and protect target organs. This article systematically discussed the TCM understanding, modern pathophysiological mechanism, and the clinical treatment strategy of kidney-tonifying drugs(single drugs and compounds) in the treatment of hypertension complicated with sexual dysfunction in order to provide a scientific basis for kidney-tonifying method in the treatment of hypertension complicated with sexual dysfunction.

摘要

高血压及其靶器官损害已成为一个主要的公共卫生问题。性功能障碍是现代高血压治疗中的一个新问题。现代病理生理学研究表明,高血压可导致性功能障碍。此外,以利尿剂为代表的三大类降压药物也可导致性功能障碍。在中医中,高血压属于“眩晕”“头痛”“头风”等范畴。过去,对高血压中医发病机制的认识主要从“肝风”和“阳亢”的角度出发。然而,基于对古今文献和医案的深入研究以及多年的临床实践,现已确定肾虚是关键发病机制。高血压合并性功能障碍属于中医肾虚证范畴,尤其是肾阴虚。其他研究小组之前的研究表明,滋阴补肾法可有效降低血压、改善性功能、逆转危险因素并保护靶器官。本文系统地探讨了中医对高血压合并性功能障碍的认识、现代病理生理机制以及补肾药物(单味药和复方)治疗高血压合并性功能障碍的临床治疗策略,以便为补肾法治疗高血压合并性功能障碍提供科学依据。

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