Chen Yen T, Murphy Susan L, Furst Daniel E, Clements Philip, Kafaja Suzanne, Tsevat Joel, Malcarne Vanessa, Khanna Dinesh
Department of Physical Medicine & Rehabilitation, University of Michigan, Ann Arbor, MI, USA.
University of Michigan Scleroderma Program, Ann Arbor, MI, USA.
J Scleroderma Relat Disord. 2023 Jun;8(2):107-112. doi: 10.1177/23971983221146366. Epub 2023 Feb 8.
Systemic sclerosis often has a significant impact on an individual's quality of life. Life satisfaction is a subjective expression of well-being and a key component of quality of life. We examined the associations between functional limitations, social support, and spiritual well-being with life satisfaction and investigated the moderating roles of social support and spiritual well-being on the relationship between functional limitations and life satisfaction in people with systemic sclerosis.
Data were drawn from the baseline University of California Los Angeles Scleroderma Quality of Life Study. Participants completed questionnaires that included demographics, depressive symptoms, functional limitations, social support, and spiritual well-being. The Satisfaction with Life Scale was used to evaluate overall life satisfaction. Data were analyzed using a hierarchical linear regression.
Of 206 participants (84% female, 74% White, 52% limited cutaneous subtype, 51% early disease), 38% reported being dissatisfied with their lives. Functional limitations (β = -0.19, = 0.006), social support (β = 0.18, = 0.006), and spiritual well-being (β = 0.40, < 0.001) were associated with life satisfaction, with spiritual well-being emerging as the strongest statistical contributor. However, social support and spiritual well-being did not significantly moderate the relationship between functional limitations and life satisfaction ( = 0.882 and = 0.339, respectively).
Spiritual well-being is particularly important in understanding life satisfaction in people with systemic sclerosis. Future longitudinal research is needed to assess and examine spiritual well-being and its impact on life satisfaction in a larger and more diverse systemic sclerosis sample.
系统性硬化症常对个体生活质量产生重大影响。生活满意度是幸福感的主观体现,也是生活质量的关键组成部分。我们研究了功能受限、社会支持和精神幸福感与生活满意度之间的关联,并调查了社会支持和精神幸福感在系统性硬化症患者功能受限与生活满意度关系中的调节作用。
数据取自加利福尼亚大学洛杉矶分校硬皮病生活质量研究的基线数据。参与者完成了包括人口统计学、抑郁症状、功能受限、社会支持和精神幸福感的问卷调查。使用生活满意度量表评估总体生活满意度。数据采用分层线性回归进行分析。
206名参与者(84%为女性,74%为白人,52%为局限性皮肤亚型,51%为疾病早期)中,38%报告对自己的生活不满意。功能受限(β = -0.19,P = 0.006)、社会支持(β = 0.18,P = 0.006)和精神幸福感(β = 0.40,P < 0.001)与生活满意度相关,其中精神幸福感是最强的统计学贡献因素。然而,社会支持和精神幸福感并未显著调节功能受限与生活满意度之间的关系(P分别为0.882和0.339)。
精神幸福感在理解系统性硬化症患者的生活满意度方面尤为重要。未来需要进行纵向研究,以在更大且更多样化的系统性硬化症样本中评估和检验精神幸福感及其对生活满意度的影响。