Khanna Dinesh, Furst Daniel E, Clements Philip J, Allanore Yannick, Baron Murray, Czirjak Lazlo, Distler Oliver, Foeldvari Ivan, Kuwana Masataka, Matucci-Cerinic Marco, Mayes Maureen, Medsger Thomas, Merkel Peter A, Pope Janet E, Seibold James R, Steen Virginia, Stevens Wendy, Denton Christopher P
University of Michigan Scleroderma Program, Ann Arbor, MI, USA.
UCLA, Los Angeles, CA, USA.
J Scleroderma Relat Disord. 2017 Jan-Apr;2(1):11-18. doi: 10.5301/jsrd.5000231.
The modified Rodnan skin score (mRSS) is a measure of skin thickness and is used as a primary or secondary outcome measure in clinical trials of systemic sclerosis (scleroderma). This state-of-art review provides a historical perspective of the development of the mRSS, summarizes the performance of mRSS as an outcome measure, provides guidance on assessing mRSS, and makes recommendations for incorporation of the mRSS into clinical trials.
改良罗德南皮肤评分（mRSS）是一种衡量皮肤厚度的指标，在系统性硬化症（硬皮病）的临床试验中用作主要或次要结局指标。本综述提供了mRSS发展的历史视角，总结了mRSS作为结局指标的表现，提供了评估mRSS的指导，并就将mRSS纳入临床试验提出了建议。
