Saksena S, Pantopoulos D, Parsonnet V, Rothbart S T, Hussain S M, Gielchinsky I
Am J Cardiol. 1986 Jul 1;58(1):70-4. doi: 10.1016/0002-9149(86)90243-2.
The Cordis Omni-Orthocor model 234A, an implantable antitachycardia system, was evaluated in 13 patients. Two patients had recurrent sustained supraventricular tachycardia (SVT) and 11 had ventricular tachycardia (VT). The system was used for SVT or VT termination (group 1: SVT, 2 patients; VT, 4 patients) or for demand pacing and noninvasive electrophysiologic studies for tachycardia induction and serial electrophysiologic testing alone (group 2: VT, 7 patients). The overdriver was used successfully in 4 of 6 patients in group 1 for repeated tachycardia termination (SVT and VT) during a mean follow-up period of 18 months. One patient had 1 sustained VT episode unresponsive to pacing and 1 patient had no recurrence of tachycardia. Tachycardia termination zones varied when using the system in 2 patients receiving long-term amiodarone therapy. Eighteen noninvasive electrophysiologic studies for serial drug testing were performed, 4 in group 1 and 14 in group 2. Clinical tachycardia was induced and successfully terminated by use of the overdriver in 12 studies. It is concluded that implantable antitachycardia systems can be used successfully for noninvasive tachycardia induction and termination and for reliable serial electrophysiologic studies. Such systems provide improved patient safety and acceptability and are reasonable in cost.
对13例患者使用了可植入式抗心动过速系统Cordis Omni-Orthocor型号234A进行评估。其中2例患者患有复发性持续性室上性心动过速(SVT),11例患有室性心动过速(VT)。该系统用于终止SVT或VT(第1组:SVT,2例患者;VT,4例患者),或用于按需起搏以及单独进行心动过速诱发的无创电生理研究和系列电生理测试(第2组:VT,7例患者)。在平均18个月的随访期内,第1组6例患者中有4例成功使用超速驱动起搏反复终止心动过速(SVT和VT)。1例患者出现1次持续性VT发作,对起搏无反应,1例患者心动过速未复发。在2例接受长期胺碘酮治疗的患者中使用该系统时,心动过速终止区域有所不同。共进行了18次用于系列药物测试的无创电生理研究,第1组4次,第2组14次。在12次研究中,通过使用超速驱动起搏成功诱发并终止了临床心动过速。结论是,可植入式抗心动过速系统可成功用于无创性心动过速的诱发和终止以及可靠的系列电生理研究。此类系统提高了患者的安全性和可接受性,且成本合理。