Wen Chenxi, Li Ting, Huang Zheng, Kang Qi-Kai
School of Chemistry and Material Sciences, Hangzhou Institute of Advanced Study, University of Chinese Academy of Sciences, 1 Sub-lane Xiangshan, Hangzhou, 310024, China.
The State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, China.
Chem Rec. 2023 Nov;23(11):e202300146. doi: 10.1002/tcr.202300146. Epub 2023 Jun 7.
Preparing valuable olefins from cheap and abundant alkane resources has long been a challenging task in organic synthesis, which mainly suffers from harsh reaction conditions and narrow scopes. Homogeneous transition metals catalyzed dehydrogenation of alkanes has attracted much attention for its excellent catalytic activities under relatively milder conditions. Among them, base metal catalyzed oxidative alkane dehydrogenation has emerged as a viable strategy for olefin synthesis for its usage of cheap catalysts, compatibility with various functional groups, and low reaction temperature. In this review, we discuss recent development of base metal catalyzed alkane dehydrogenation under oxidative conditions and their application in constructing complex molecules.
从廉价且丰富的烷烃资源制备有价值的烯烃长期以来一直是有机合成中的一项具有挑战性的任务，这主要受制于苛刻的反应条件和狭窄的适用范围。均相过渡金属催化的烷烃脱氢反应因其在相对温和的条件下具有优异的催化活性而备受关注。其中，碱金属催化的氧化烷烃脱氢反应因其使用廉价催化剂、与各种官能团的兼容性以及较低的反应温度，已成为一种可行的烯烃合成策略。在本综述中，我们讨论了碱金属催化的氧化条件下烷烃脱氢反应的最新进展及其在构建复杂分子中的应用。
