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孟加拉国炎症性肠病患者的生活质量

Quality of Life of Patients With Inflammatory Bowel Disease in Bangladesh.

作者信息

Ghosh Chanchal Kumar, Islam Sumona, Tabassum Nowrin, Mohiuddin Syed Arafat, Hossain Md Mosarrof, Sarkar Aditi, Bari Amit

机构信息

Department of Gastroenterology, Bangabandhu Sheikh Mujib Medical University, Dhaka, BGD.

Department of Nephrology, Kidney Foundation Hospital and Research Institute, Dhaka, BGD.

出版信息

Cureus. 2023 Jun 4;15(6):e39929. doi: 10.7759/cureus.39929. eCollection 2023 Jun.

Abstract

Introduction The importance of maintaining quality of life in managing inflammatory bowel disease (IBD) has increased in recent years. However, there is a lack of studies examining the health-related quality of life (HRQoL) of IBD patients in Bangladesh. Methodology This cross-sectional study was carried out in the IBD clinic, Bangabandhu Sheikh Mujib Medical University (BSMMU) from 2020 to 2022. Data were collected from both ulcerative colitis (UC) and Crohn's disease (CD) patients. HRQoL was recorded on the EuroQol 5 Dimension 5 Level (EQ-5D-5L) questionnaire. Statistical analysis was done by Statistical Analysis Software (SAS, SAS Institute, Cary, NC). Results The mean age was 36.3 years. The majority of the patients were male and had low incomes. People with more monthly income, more frequent relapse, extraintestinal involvement, and moderate to severe disease had lower utility index (p = 0.01, 0.01, 0.0004, and <0.0001, respectively). Among the five individual components, only usual activity was lower in UC patients (p = 0.03); all the other components and consequently the overall utility index did not vary between UC and CD. The visual analog scale (VAS) score seemed to be comparable in UC and CD patients. Conclusion In more severe and frequently relapsing cases of IBD, the utility index representing HRQoL was found to be lower. Comparatively, the HRQoL was mostly similar between patients with UC and CD. Additionally, the mean utility score in IBD patients was higher than that observed in patients with type 2 diabetes mellitus in Bangladesh.

摘要

引言 近年来,在炎症性肠病(IBD)管理中维持生活质量的重要性日益增加。然而,孟加拉国缺乏对IBD患者健康相关生活质量(HRQoL)的研究。

方法 本横断面研究于2020年至2022年在班加班杜·谢赫·穆吉布医科大学(BSMMU)的IBD诊所进行。数据收集自溃疡性结肠炎(UC)和克罗恩病(CD)患者。HRQoL通过欧洲五维度五水平健康量表(EQ-5D-5L)问卷记录。统计分析使用统计分析软件(SAS,SAS Institute,卡里,北卡罗来纳州)完成。

结果 平均年龄为36.3岁。大多数患者为男性且收入较低。月收入较高、复发更频繁、有肠外表现以及疾病为中度至重度的患者效用指数较低(分别为p = 0.01、0.01、0.0004和<0.0001)。在五个单项中,只有UC患者的日常活动较低(p = 0.03);UC和CD患者在所有其他单项以及总体效用指数方面没有差异。视觉模拟量表(VAS)评分在UC和CD患者中似乎相当。

结论 在更严重且复发频繁的IBD病例中,代表HRQoL的效用指数较低。相比之下,UC和CD患者的HRQoL大多相似。此外,孟加拉国IBD患者的平均效用得分高于2型糖尿病患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1445/10239544/576324b7bba6/cureus-0015-00000039929-i01.jpg

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