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孟加拉国 2 型糖尿病患者的健康相关生活质量及其预测因素:一项全国性横断面研究。

Health-related quality of life and its predictors among the type 2 diabetes population of Bangladesh: A nation-wide cross-sectional study.

机构信息

Department of Non-communicable Diseases, Bangladesh University of Health Sciences (BUHS), Dhaka, Bangladesh.

Department of Biostatistics, Bangladesh University of Health Sciences (BUHS), Dhaka, Bangladesh.

出版信息

J Diabetes Investig. 2021 Feb;12(2):277-285. doi: 10.1111/jdi.13331. Epub 2020 Aug 3.

DOI:10.1111/jdi.13331
PMID:32564501
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7858106/
Abstract

AIMS/INTRODUCTION: We aimed to assess the health-related quality of life (HRQoL) and identify its predictors among type 2 diabetes patients of Bangladesh.

MATERIALS AND METHODS

This nationwide cross-sectional study assessed HRQoL among 1,806 type 2 diabetes patients using the EuroQol-5 Dimensions Questionnaire (EQ-5D-5L), and the responses were further translated into a single summary crosswalk index score using the UK time trade-off value set. The predictors were determined using multinomial logistic regression analysis.

RESULTS

The mean EQ-5D-5L index score was 0.62 (standard deviation 0.25), and men scored better than women. More than half of the study participants (53.4%) were ranked as "average" HRQoL. Overall, 64% of respondents had a "problem" at least in one of the dimensions of the EQ-5D-5L, and the burden of reported "problems" was higher among women (70%). Among the five dimensions, the highest reported "problem" was 79.8% for anxiety/depression, 77.7% for pain/discomfort and 60.1% for mobility. However, younger participants (aged <30 years) showed a higher burden of anxiety/depression (95%) compared with the rest of the population. The specific predictors of average/good HRQoL (odds ratio >1) were being men, living in a rural area, married, literate, a monthly income >19,488 BDT, absence of comorbidity and had a duration of diabetes ≤5 years.

CONCLUSIONS

The majority of Bangladesh's type 2 diabetes patients had an "average" HRQoL based on the EQ-5D-5L index score. In broad terms, the identified predictors were sex, place of residence, marital status, literacy, monthly income, comorbidity and duration of diabetes.

摘要

目的/引言:本研究旨在评估孟加拉国 2 型糖尿病患者的健康相关生活质量(HRQoL),并确定其预测因素。

材料和方法

本全国性横断面研究使用欧洲五维健康量表问卷(EQ-5D-5L)评估了 1806 名 2 型糖尿病患者的 HRQoL,并用英国时间权衡值集将反应进一步转化为单一的综合交叉指数评分。使用多项逻辑回归分析确定预测因素。

结果

EQ-5D-5L 指数平均得分为 0.62(标准差 0.25),男性得分优于女性。超过一半的研究参与者(53.4%)被评为“平均”HRQoL。总体而言,64%的受访者在 EQ-5D-5L 的至少一个维度上存在“问题”,且女性报告的“问题”负担更高(70%)。在五个维度中,报告的“问题”最高的是焦虑/抑郁(79.8%)、疼痛/不适(77.7%)和行动能力(60.1%)。然而,年轻参与者(年龄<30 岁)比其他人群报告的焦虑/抑郁负担更高(95%)。平均/良好 HRQoL 的特定预测因素(比值比>1)是男性、居住在农村地区、已婚、识字、月收入>19488 孟加拉塔卡、无合并症且糖尿病病程≤5 年。

结论

根据 EQ-5D-5L 指数评分,孟加拉国大多数 2 型糖尿病患者的 HRQoL 为“平均”。总体而言,确定的预测因素包括性别、居住地点、婚姻状况、文化程度、月收入、合并症和糖尿病病程。

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