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[呼吸力学对血细胞比容的影响。III. 对接受间歇正压吸入疗法治疗的支气管肺部疾病患者的研究]

[The effect of respiratory mechanics on the hematocrit. III. Study in patients with bronchopulmonary disease treated with intermittent positive pressure inhalation therapy].

作者信息

Fumagalli G, Della Torre F, Sunseri S, Numeroso R, Ferrara A

出版信息

Minerva Med. 1979 Jan 7;70(1):59-65.

PMID:372847
Abstract

The Authors studied the behaviour of lung volumes and mechanics and of haematocrit after intermittent pulmonary positive pressure breathing (IPPB) in patients with chronic obstructive lung disease. An improvement of obstructive sindrome at 10'-20'-40' and a contemporary decreasing of haematocrit were observed. This statistically significant modification was regarded as an expression of a different distribution of blood in lung vessels dued to an increasing of this vascular compliance and to a decrease of alveolar inflation. The Authors postulate the realization of a better circulation in lung vessels which contributes to a lowering of haematocrit in these patients perhaps for a different VA/Ob ratio.

摘要

作者研究了慢性阻塞性肺疾病患者在间歇性肺正压通气(IPPB)后肺容积、力学及血细胞比容的变化。观察到在10分钟、20分钟、40分钟时阻塞综合征有所改善,同时血细胞比容降低。这种具有统计学意义的改变被认为是由于肺血管顺应性增加和肺泡膨胀减少导致肺血管内血液分布不同的一种表现。作者推测肺血管中实现了更好的循环,这可能是由于不同的通气/血流比值,从而有助于降低这些患者的血细胞比容。

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