Zimmermann H, Brändli O
Schweiz Med Wochenschr. 1980 Feb 9;110(6):232-6.
Retrospective analysis of the influence of therapy on the course of chronic obstructive lung disease in 71 patients over 3 years showed that cessation of smoking, long-term therapy with corticosteroids and IPPB-therapy did not significantly alter the functional deterioration. The average annual FEV decline of 68 ml ((initial FEV 1.28 +/- 0.661) is comparable with the results of other authors. The importance of controlled, prospective therapeutic trials is stressed.
对71例患者进行的为期3年的慢性阻塞性肺疾病治疗影响的回顾性分析表明,戒烟、长期使用皮质类固醇治疗和间歇性正压通气治疗并未显著改变功能恶化情况。平均每年FEV下降68毫升(初始FEV为1.28 +/- 0.661),这与其他作者的结果相当。强调了进行对照性前瞻性治疗试验的重要性。