Pe'er J, Hidayat A A
Am J Ophthalmol. 1986 Jul 15;102(1):80-6. doi: 10.1016/0002-9394(86)90213-8.
Fourteen cases of rare conjunctival myxoma were studied clinicopathologically. The median age of the eight men and six women was 50 years (range, 18 to 76 years). The tumors appeared as slowly growing, freely movable solitary lesions located primarily in the temporal bulbar conjunctiva. The clinical diagnosis was cyst in many cases. The lesions were removed by simple local excision and did not recur. Histologically, they were hypocellular and were composed of stellate and spindle-shaped cells; some had small intracytoplasmic and intranuclear vacuoles. The stroma contained abundant mucoid material and sparse reticulin and delicate collagen fibers. Scattered mast cells were found in many lesions. Ultrastructurally, the intracytoplasmic vacuoles appeared to be extremely dilated cisternae of rough-surfaced endoplasmic reticulum. Invaginations of the nuclear membrane by the cytoplasm correlated with intranuclear vacuoles seen by light microscopy. Conjunctival myxomas are benign tumors and should be differentiated from other benign and malignant soft-tissue tumors with myxomatous features.
对14例罕见的结膜黏液瘤进行了临床病理研究。8名男性和6名女性的中位年龄为50岁（范围18至76岁）。肿瘤表现为生长缓慢、可自由移动的孤立性病变，主要位于颞侧球结膜。许多病例的临床诊断为囊肿。通过简单的局部切除将病变切除，未复发。组织学上，它们细胞稀少，由星状和梭形细胞组成；一些细胞有小的胞质内和核内空泡。间质含有丰富的黏液样物质、稀疏的网状纤维和纤细的胶原纤维。许多病变中发现有散在的肥大细胞。超微结构上，胞质内空泡似乎是粗面内质网极度扩张的池。细胞质对核膜的内陷与光镜下所见的核内空泡相关。结膜黏液瘤是良性肿瘤，应与其他具有黏液瘤特征的良性和恶性软组织肿瘤相鉴别。
