• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

成人和青少年饮食失调症的治疗概述:药理学与心理治疗

An overview of the treatment of eating disorders in adults and adolescents: pharmacology and psychotherapy.

作者信息

Costandache Gina I, Munteanu Oana, Salaru Andra, Oroian Bianca, Cozmin Mihai

机构信息

Department of Adult Psychiatry, Institute of Psychiatry "Socola", Iași, Romania.

Clinical Emergency Hospital for Children, Child and Adolescent Psychiatry Clinic, Cluj-Napoca, Romania.

出版信息

Postep Psychiatr Neurol. 2023 Mar;32(1):40-48. doi: 10.5114/ppn.2023.127237. Epub 2023 May 8.

DOI:10.5114/ppn.2023.127237
PMID:37287736
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10243293/
Abstract

PURPOSE

This article provides an overview of current treatment options for adults and adolescents suffering from eating disorders (ED).

VIEWS

ED are prevalent public health problems that considerably impair physical health and disrupt psychosocial functioning. In primary care settings, anorexia nervosa, bulimia nervosa, and binge eating disorder represent the most frequently seen types of eating disorders, in both adults and adolescents. To address these maladaptive eating-related behaviors and concurrent psychiatric symptoms, various pharmacological interventions and specialized psychological treatments have been evaluated and received support to varying degrees by controlled research.

CONCLUSIONS

The current literature regarding children and adolescents with eating disorders mainly supports the use of psychological interventions, such as family-based treatment and cognitive behavioral therapy. Due to the lack of robust evidence, the use of psychotropic medications is neither recommended nor approved in this population. For adults with eating disorders, an array of behaviorally focused psychotherapies, along with integrative and interpersonal approaches, can lead to the improvement of symptoms and the achievement of a healthy weight. Moreover, aside from psychotherapy, several pharmacological agents can contribute to the alleviation of eating disorders' clinical characteristics in the adult population. At the moment, the recommended psychotropic medication for eating disorders is represented by fluoxetine for bulimia nervosa and lisdexamfetamine for binge eating disorder.

摘要

目的

本文概述了患有饮食失调(ED)的成人和青少年目前的治疗选择。

观点

饮食失调是普遍存在的公共卫生问题,会严重损害身体健康并扰乱心理社会功能。在初级保健环境中,神经性厌食症、神经性贪食症和暴饮暴食症是成人和青少年中最常见的饮食失调类型。为了应对这些与饮食相关的适应不良行为和并发的精神症状,各种药物干预和专门的心理治疗已经得到评估,并在对照研究中得到了不同程度的支持。

结论

目前关于患有饮食失调的儿童和青少年的文献主要支持使用心理干预,如基于家庭的治疗和认知行为疗法。由于缺乏有力证据,不建议也未批准在该人群中使用精神药物。对于患有饮食失调的成年人,一系列以行为为重点的心理治疗,以及综合和人际方法,可以改善症状并实现健康体重。此外,除了心理治疗外,几种药物制剂可以有助于减轻成人人群中饮食失调的临床特征。目前,推荐用于饮食失调的精神药物是用于神经性贪食症的氟西汀和用于暴饮暴食症的赖氨酸右旋苯丙胺。

相似文献

1
An overview of the treatment of eating disorders in adults and adolescents: pharmacology and psychotherapy.成人和青少年饮食失调症的治疗概述:药理学与心理治疗
Postep Psychiatr Neurol. 2023 Mar;32(1):40-48. doi: 10.5114/ppn.2023.127237. Epub 2023 May 8.
2
Psychotherapy for bulimia nervosa and binging.神经性贪食症和暴饮暴食的心理治疗
Cochrane Database Syst Rev. 2003(1):CD000562. doi: 10.1002/14651858.CD000562.
3
Psychotherapy for bulimia nervosa and binging.神经性贪食症和暴饮暴食的心理治疗。
Cochrane Database Syst Rev. 2004(3):CD000562. doi: 10.1002/14651858.CD000562.pub2.
4
5
Psychotherapy for bulimia nervosa and binging.神经性贪食症和暴饮暴食的心理治疗。
Cochrane Database Syst Rev. 2001(3):CD000562. doi: 10.1002/14651858.CD000562.
6
Psychotherapy for bulimia nervosa and binging.神经性贪食症和暴饮暴食的心理治疗。
Cochrane Database Syst Rev. 2000(4):CD000562. doi: 10.1002/14651858.CD000562.
7
Psychotherapy and Medications for Eating Disorders: Better Together?饮食失调的心理治疗与药物治疗:二者结合效果更佳?
Clin Ther. 2021 Jan;43(1):17-39. doi: 10.1016/j.clinthera.2020.10.006. Epub 2020 Dec 18.
8
Psychosocial and pharmacological treatment of eating disorders: a review of research findings.饮食失调的心理社会及药物治疗:研究结果综述
J Clin Psychol. 1999 Jun;55(6):685-97. doi: 10.1002/(sici)1097-4679(199906)55:6<685::aid-jclp3>3.0.co;2-y.
9
Cognitive Behavioral Therapy for the Eating Disorders.认知行为疗法治疗进食障碍。
Annu Rev Clin Psychol. 2021 May 7;17:417-438. doi: 10.1146/annurev-clinpsy-081219-110907.
10
Psychotherapies for eating disorders: findings from a rapid review.饮食失调的心理治疗:快速综述的结果
J Eat Disord. 2023 Oct 4;11(1):175. doi: 10.1186/s40337-023-00886-w.

引用本文的文献

1
Engineered Hydrogels for Musculoskeletal Regeneration: Advanced Synthesis Strategies and Therapeutic Efficacy in Preclinical Models.用于肌肉骨骼再生的工程水凝胶:临床前模型中的先进合成策略与治疗效果
Polymers (Basel). 2025 Jul 30;17(15):2094. doi: 10.3390/polym17152094.
2
Noninvasive Brain Stimulation as a Novel Treatment Approach for Anorexia Nervosa: A Meta-analysis and Systematic Review of Literature.无创脑刺激作为神经性厌食症的一种新型治疗方法:一项文献的荟萃分析和系统评价
Indian J Psychol Med. 2025 Jul 2:02537176251351253. doi: 10.1177/02537176251351253.
3
The impact of glucagon-like peptide-1 (GLP-1) agonists in the treatment of eating disorders: a systematic review and meta-analysis.胰高血糖素样肽-1(GLP-1)激动剂在饮食失调治疗中的作用:一项系统评价和荟萃分析。
Eat Weight Disord. 2025 Feb 1;30(1):10. doi: 10.1007/s40519-025-01720-9.
4
Psychopharmacology Review for Eating Disorders Among Children, Adolescents, and Adults.儿童、青少年和成人饮食失调的精神药理学综述
Focus (Am Psychiatr Publ). 2024 Jul;22(3):307-311. doi: 10.1176/appi.focus.20230043. Epub 2024 Jun 28.
5
Shared Genetic Architecture Between Schizophrenia and Anorexia Nervosa: A Cross-trait Genome-Wide Analysis.精神分裂症与神经性厌食症的共享遗传结构:跨表型全基因组分析。
Schizophr Bull. 2024 Aug 27;50(5):1255-1265. doi: 10.1093/schbul/sbae087.

本文引用的文献

1
Antipsychotics in the Treatment of Children and Adolescents with Anorexia Nervosa: A Systematic Review.抗精神病药物治疗神经性厌食症儿童和青少年:一项系统综述。
Biomedicines. 2022 Dec 7;10(12):3167. doi: 10.3390/biomedicines10123167.
2
Lisdexamfetamine and binge-eating disorder: A systematic review and meta-analysis of the preclinical and clinical data with a focus on mechanism of drug action in treating the disorder.利司扑胺与暴食症:基于临床前和临床数据的系统评价和荟萃分析,重点关注药物治疗该疾病的作用机制。
Eur Neuropsychopharmacol. 2021 Dec;53:49-78. doi: 10.1016/j.euroneuro.2021.08.001. Epub 2021 Aug 27.
3
Incidence, prevalence and mortality of anorexia nervosa and bulimia nervosa.神经性厌食症和神经性贪食症的发病率、患病率和死亡率。
Curr Opin Psychiatry. 2021 Nov 1;34(6):515-524. doi: 10.1097/YCO.0000000000000739.
4
An update on the prevalence of eating disorders in the general population: a systematic review and meta-analysis.一般人群中进食障碍患病率的最新研究进展:系统评价和荟萃分析。
Eat Weight Disord. 2022 Mar;27(2):415-428. doi: 10.1007/s40519-021-01162-z. Epub 2021 Apr 8.
5
Is aripiprazole a key to unlock anorexia nervosa?: A case series.阿立哌唑是解开神经性厌食症之谜的关键吗?:病例系列
Clin Case Rep. 2020 Sep 6;8(12):2827-2834. doi: 10.1002/ccr3.3271. eCollection 2020 Dec.
6
State of the Art: The Therapeutic Approaches to Bulimia Nervosa.最新进展:神经性贪食症的治疗方法
Clin Ther. 2021 Jan;43(1):40-49. doi: 10.1016/j.clinthera.2020.10.012. Epub 2020 Dec 23.
7
Current Therapeutic Approaches to Anorexia Nervosa: State of the Art.目前神经性厌食症的治疗方法:最新进展。
Clin Ther. 2021 Jan;43(1):85-94. doi: 10.1016/j.clinthera.2020.11.006. Epub 2020 Dec 5.
8
Pharmacological treatment of eating disorders, comorbid mental health problems, malnutrition and physical health consequences.进食障碍的药物治疗,合并的心理健康问题、营养不良和身体健康后果。
Pharmacol Ther. 2021 Jan;217:107667. doi: 10.1016/j.pharmthera.2020.107667. Epub 2020 Aug 25.
9
Developments in the psychological treatment of anorexia nervosa and their implications for daily practice.神经性厌食症的心理治疗进展及其对日常实践的启示。
Curr Opin Psychiatry. 2020 Nov;33(6):534-541. doi: 10.1097/YCO.0000000000000642.
10
Anorexia nervosa in adolescents.青少年神经性厌食症。
Br J Hosp Med (Lond). 2020 Jun 2;81(6):1-8. doi: 10.12968/hmed.2020.0099. Epub 2020 Jun 1.