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神经性贪食症和暴饮暴食的心理治疗。

Psychotherapy for bulimia nervosa and binging.

作者信息

Hay P J, Bacaltchuk J, Stefano S

机构信息

Psychiatry, School of Medicine, James Cook University, School of Medicine, James Cook University, Townsville, Queensland, Australia, 4811.

出版信息

Cochrane Database Syst Rev. 2004(3):CD000562. doi: 10.1002/14651858.CD000562.pub2.

Abstract

BACKGROUND

Bulimia nervosa and related syndromes such as binge eating disorder are common in young Western women. A specific manual-based form of cognitive behaviour therapy (CBT) has been developed for the treatment of bulimia nervosa (CBT-BN). Other psychotherapies, some from a different theoretical framework, and some modifications of CBT are also used.

OBJECTIVES

To evaluate the efficacy of CBT and CBT-BN and compare them with other psychotherapies in the treatment of adults with bulimia nervosa or related syndromes of recurrent binge eating.

SEARCH STRATEGY

A handsearch of The International Journal of Eating Disorders since its first issue; database searches of MEDLINE, EXTRAMED, EMBASE, PsycInfo, CURRENT CONTENTS, LILACS, SCISEARCH, CENTRAL and the The Cochrane Collaboration Depression, Anxiety & Neurosis Controlled Trials Register; citation list searching and personal approaches to authors were used.

SELECTION CRITERIA

All studies that have tested any form of psychotherapy for adults with non-purging bulimia nervosa, binge eating disorder and/or other types of eating disorders of a bulimic type (eating disorder, not otherwise specified, or EDNOS), and which applied a randomised controlled and standardised outcome methodology.

DATA COLLECTION AND ANALYSIS

Data were analysed using the Review Manager software program. Relative risks were calculated for binary outcome data. Standardized mean differences were calculated for continuous variable outcome data. A fixed effects model was used to analyse the data. Sensitivity analyses of a number of measures of trial quality were conducted. Data were not reported in such a way to permit subgroup analyses, but the effects of treatment on depressive symptoms, psychosocial and/or interpersonal functioning, general psychiatric symptoms and weight were examined where possible. Funnel plots were drawn to investigate the presence of publication bias.

MAIN RESULTS

The review supported the efficacy of cognitive-behavioural psychotherapy (CBT) and particularly CBT-BN in the treatment of people with bulimia nervosa and also (but less strongly due to the small number of trials) related eating disorder syndromes. CBT was also shown to be effective in group settings. Other psychotherapies were also efficacious, particularly interpersonal psychotherapy in the longer-term. Self-help approaches that used highly structured CBT treatment manuals, were promising albeit with more modest results generally, and their evaluation in bulimia nervosa merits further research. Exposure and Response Prevention did not appear to enhance the efficacy of CBT.Psychotherapy alone is unlikely to reduce or change body weight in people with bulimia nervosa or similar eating disorders.

REVIEWERS' CONCLUSIONS: There is a small body of evidence for the efficacy of cognitive-behaviour therapy in bulimia nervosa and similar syndromes, but the quality of trials is very variable and sample sizes are often small. More trials of CBT are needed, particularly for binge eating disorder and other EDNOS syndromes. Trials evaluating other psychotherapies and less intensive psychotherapies should also be conducted.

摘要

背景

神经性贪食症及相关综合征,如暴饮暴食症,在西方年轻女性中很常见。一种基于特定手册的认知行为疗法(CBT)已被开发用于治疗神经性贪食症(CBT-BN)。其他心理疗法也被使用,其中一些来自不同的理论框架,还有一些是CBT的变体。

目的

评估CBT和CBT-BN在治疗患有神经性贪食症或复发性暴饮暴食相关综合征的成年人中的疗效,并将它们与其他心理疗法进行比较。

检索策略

自《国际进食障碍杂志》创刊以来对其进行手工检索;对MEDLINE、EXTRAMED、EMBASE、PsycInfo、《现刊目次》、LILACS、SCISEARCH、CENTRAL以及Cochrane协作网抑郁、焦虑与神经症对照试验注册库进行数据库检索;使用引文列表检索并通过个人途径联系作者。

入选标准

所有测试过任何形式心理疗法治疗非清除型神经性贪食症、暴饮暴食症和/或其他贪食型饮食失调(未另行说明的饮食失调,或EDNOS)成年患者的研究,且这些研究采用了随机对照和标准化结局方法。

数据收集与分析

使用Review Manager软件程序分析数据。计算二分类结局数据的相对风险。计算连续变量结局数据的标准化均数差。采用固定效应模型分析数据。对多项试验质量指标进行敏感性分析。数据报告方式不允许进行亚组分析,但在可能的情况下检查了治疗对抑郁症状、心理社会和/或人际功能、一般精神症状及体重的影响。绘制漏斗图以调查发表偏倚的存在情况。

主要结果

该综述支持认知行为心理疗法(CBT),尤其是CBT-BN在治疗神经性贪食症患者中的疗效,对于相关饮食失调综合征也有疗效(但由于试验数量少,支持力度稍弱)。CBT在团体治疗环境中也被证明是有效的。其他心理疗法也有效,尤其是长期的人际心理疗法。使用高度结构化CBT治疗手册的自助方法很有前景,尽管总体结果较为一般,对其在神经性贪食症中的评估值得进一步研究。暴露与反应预防似乎并未增强CBT的疗效。单纯心理治疗不太可能减轻或改变神经性贪食症或类似饮食失调患者的体重。

综述作者结论

有少量证据支持认知行为疗法在神经性贪食症及类似综合征中的疗效,但试验质量差异很大,样本量通常较小。需要更多CBT试验,尤其是针对暴饮暴食症和其他EDNOS综合征的试验。还应开展评估其他心理疗法和强度较低心理疗法的试验。

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