Suppr超能文献

与标准喂养相比,血流动力学稳定的极低出生体重新生儿的体重增加受早期开始完全肠内喂养的影响。

Hemodynamically stable very low birth neonates weight gain is affected by the early initiation of full enteral feedings compared to standard feeding.

作者信息

Raman Sasikumar Banahatty, Muthusamy Senthil Kumar, Mohideen Azarudeen Kadhar

机构信息

Department of Paediatrics, Government Medical College Coimbatore, Tamil Nadu, India.

Department of Paediatrics, Government Medical College, Tiruppur, Tamil Nadu, India.

出版信息

J Educ Health Promot. 2023 Mar 31;12:86. doi: 10.4103/jehp.jehp_1110_22. eCollection 2023.

Abstract

BACKGROUND

Premature babies need to develop similarly to fetuses of the same gestational age. The majority of premature neonates experience a growth-restricted status while in the patent ductus arteriosus (PDA). Extrauterine growth failure is a significant barrier for infants with very low birth weight (VLBW).

MATERIALS AND METHODS

The study was conducted for six months at the Neonatology Unit, Department of Pediatrics, Coimbatore Medical College Hospital, Coimbatore, Tamil Nadu, India. Neonates with VLBW who met the inclusion criteria were assigned randomly to one of two feeding strategies, that is, full enteral feeding or partial feeding, based on the randomization sequence discovered by opening the sealed cover. The duration of stay, weight variation, neonatal variables, feeding intolerance, necrotizing enterocolitis (NEC), septicemia, apnea, newborn hyperbilirubinemia, PDA, hypoglycemia, intracranial bleeding, and mortality of neonatal recruits were all carefully evaluated.

RESULTS

Two thousand two hundred eighty-four neonates were hospitalized throughout the six-month trial period, and 408 had low birth weight. Three hundred forty-two babies were eliminated from the study due to hemodynamic instability, persistent respiratory distress, infections, metabolic issues, and congenital abnormalities. Sixty-six babies met the study's inclusion criteria, and thus participated in the study. Sixty-six newborns weighed between 1.251 and 1.500 kg. Randomly assigning intervention and control groups. Thirty-three newborns were assigned to group A (intervention) and another 33 to group B (control).

CONCLUSIONS

The study concluded that enteral feeding was effective, inexpensive, secure, and feasible. Early full enteral feeding reduced septicemia and infant hyperbilirubinemia. Thus, we must start enteral feeding as soon as possible to avoid inadequate nutrition in neonates with VLBW during a crucial growth period.

摘要

背景

早产儿需要与相同孕周的胎儿发育情况相似。大多数早产新生儿在动脉导管未闭(PDA)期间会出现生长受限状态。宫外生长发育迟缓是极低出生体重(VLBW)婴儿面临的一个重大障碍。

材料与方法

该研究在印度泰米尔纳德邦哥印拜陀市哥印拜陀医学院医院儿科新生儿科进行了六个月。符合纳入标准的极低出生体重新生儿根据打开密封封套发现的随机序列被随机分配到两种喂养策略之一,即全肠内喂养或部分喂养。仔细评估了新生儿招募对象的住院时间、体重变化、新生儿变量、喂养不耐受、坏死性小肠结肠炎(NEC)、败血症、呼吸暂停、新生儿高胆红素血症、动脉导管未闭、低血糖、颅内出血和死亡率。

结果

在为期六个月的试验期内,共有2284名新生儿住院,其中408名出生体重低。由于血流动力学不稳定、持续性呼吸窘迫、感染、代谢问题和先天性异常,342名婴儿被排除在研究之外。66名婴儿符合研究纳入标准,因此参与了研究。66名新生儿体重在1.251至1.500千克之间。随机分为干预组和对照组。33名新生儿被分配到A组(干预组),另外33名被分配到B组(对照组)。

结论

该研究得出结论,肠内喂养有效、廉价、安全且可行。早期全肠内喂养可降低败血症和婴儿高胆红素血症。因此,我们必须尽快开始肠内喂养,以避免极低出生体重新生儿在关键生长时期出现营养不足。

相似文献

2
Trophic feedings for parenterally fed infants.经肠道营养在肠外营养婴儿中的应用。
Cochrane Database Syst Rev. 2005 Jul 20(3):CD000504. doi: 10.1002/14651858.CD000504.pub2.

本文引用的文献

4
Human milk composition: nutrients and bioactive factors.人乳成分:营养成分和生物活性因子。
Pediatr Clin North Am. 2013 Feb;60(1):49-74. doi: 10.1016/j.pcl.2012.10.002.
5
Gut microbiota in preterm infants: assessment and relevance to health and disease.早产儿的肠道微生物群:评估及其与健康和疾病的相关性。
Arch Dis Child Fetal Neonatal Ed. 2013 Jul;98(4):F286-90. doi: 10.1136/archdischild-2012-302134. Epub 2012 Sep 25.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验