Department of Surgery, Radboud University Medical Center.
Department of Surgery, Canisius-Wilhelmina Hospital, Nijmegen.
Int J Surg. 2023 Aug 1;109(8):2185-2195. doi: 10.1097/JS9.0000000000000471.
ASBO is a frequent abdominal surgical emergency and a leading cause of morbidity and mortality in emergency surgery. The aim of this study is to provide insight into the current management of adhesive small bowel obstruction (ASBO) and associated outcomes.
A nationwide prospective cross-sectional cohort study was conducted. All patients with clinical signs of ASBO admitted to participating Dutch hospitals were included during a 6 months inclusion period between April 2019 and December 2020. Ninety-day clinical outcomes were described and compared for nonoperative management (NOM) and laparoscopic and open surgery.
In 34 participating hospitals, 510 patients were included, of whom 382 (74.9%) had a definitive diagnosis of ASBO. Initial management consisted of emergency surgery in 71 (18.6%) patients and NOM in 311 (81.4%) patients, 119 (31.1%) of whom required delayed surgery after failure of NOM. Surgical interventions started laparoscopically in 51.1%, of which 36.1% were converted to laparotomy. Intentional laparoscopy resulted in shorter hospital stays compared with open surgery (median 8.0 vs. 11.0 days; P <0.001) and comparable hospital mortality (5.2 vs. 4.3%; P =1.000). Oral water-soluble contrast use was associated with a decreased length of stay ( P =0.0001). Hospital stay for surgical patients was shorter in patients who were operated on within 72 h of admission ( P <0.001).
This nationwide cross-sectional study demonstrates shorter hospital stay in ASBO patients who received water-soluble contrast, were operated within 72 h of admission or were operated with minimally invasive techniques. Results may support the standardization of ASBO treatment.
粘连性小肠梗阻(ASBO)是一种常见的腹部外科急症,也是急诊外科发病率和死亡率的主要原因。本研究旨在深入了解粘连性小肠梗阻(ASBO)的当前治疗方法及相关结果。
本研究开展了一项全国范围的前瞻性横断面队列研究。在 2019 年 4 月至 2020 年 12 月的 6 个月纳入期间,将所有有 ASBO 临床症状的患者纳入参与荷兰医院的研究。描述并比较了非手术治疗(NOM)与腹腔镜和剖腹手术的 90 天临床结果。
在 34 家参与医院中,共纳入 510 例患者,其中 382 例(74.9%)明确诊断为 ASBO。初始治疗包括 71 例(18.6%)患者行急诊手术和 311 例(81.4%)患者行 NOM,其中 119 例(31.1%)NOM 失败后需要延期手术。手术干预开始时,51.1%采用腹腔镜,其中 36.1%转为剖腹手术。与开腹手术相比,意向性腹腔镜手术可缩短住院时间(中位数 8.0 天 vs. 11.0 天;P<0.001),且院内死亡率相当(5.2% vs. 4.3%;P=1.000)。口服水溶性对比剂的使用与住院时间缩短相关(P=0.0001)。入院后 72 小时内接受手术的患者的住院时间更短(P<0.001)。
这项全国性的横断面研究表明,接受水溶性对比剂治疗、入院后 72 小时内手术或采用微创手术的 ASBO 患者住院时间更短。结果可能支持粘连性小肠梗阻治疗的标准化。