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猴痘更新:临床表现、疫苗接种指导和管理。

Mpox Update: Clinical Presentation, Vaccination Guidance, and Management.

机构信息

Icahn School of Medicine at Mount Sinai, New York, New York. Dr. Cices, Ms. Prasad, Ms. Akselrad, and Dr. Silverberg are from the Department of Dermatology; Drs. Sells, Woods, and Camins are from the Division of Infectious Diseases; and Dr. Silverberg also is from the Department of Pediatrics.

出版信息

Cutis. 2023 Apr;111(4):197-202. doi: 10.12788/cutis.0745.

DOI:10.12788/cutis.0745
PMID:37289697
Abstract

Following the eradication of smallpox, intermittent small outbreaks of mpox (monkeypox) have occurred with increasing frequency, primarily in endemic regions of Africa. With the rapid spread of mpox around the globe in 2022, we are approaching a second zoonotic pandemic of the 21st century. Given the predominance of cutaneous involvement in mpox, dermatologists should be prepared to recognize the clinical features and manage this increasingly prevalent disease. This article reviews a brief history of the mpox virus, clinical presentation, complications, approach to diagnosis, methods of transmission, infection control recommendations, indications for vaccination, and therapeutic options to inform dermatologists on the frontline of the mpox epidemic.

摘要

在消灭天花之后,猴痘(猴痘病毒)间歇性小爆发的频率越来越高,主要发生在非洲流行地区。随着 2022 年猴痘在全球的迅速传播,我们正面临 21 世纪的第二次人畜共患病大流行。鉴于猴痘主要累及皮肤,皮肤科医生应准备好识别其临床特征并对此日益流行的疾病进行管理。本文回顾了猴痘病毒的简史、临床表现、并发症、诊断方法、传播方式、感染控制建议、疫苗接种指征和治疗选择,以期为处于猴痘疫情一线的皮肤科医生提供信息。

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Afr J Lab Med. 2025 May 31;14(1):2644. doi: 10.4102/ajlm.v14i1.2644. eCollection 2025.
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Clinical Predictors and Determinants of Mpox Complications in Hospitalized Patients: A Prospective Cohort Study from Burundi.住院患者猴痘并发症的临床预测因素和决定因素:来自布隆迪的一项前瞻性队列研究
Viruses. 2025 Mar 27;17(4):480. doi: 10.3390/v17040480.
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"I Know They're Going to Weaponize This:" Black and Latino Sexual Minority Men's Mpox-Related Sexual Behaviors, Stigma Concerns, and Vaccination Barriers and Facilitators.
“我知道他们会将此武器化”:黑人及拉丁裔性少数男性与猴痘相关的性行为、耻辱感担忧以及疫苗接种的障碍与促进因素
J Racial Ethn Health Disparities. 2025 Apr 4. doi: 10.1007/s40615-025-02404-x.
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Personalized immunization against Mpox Clades I and Ib: Strategies to combat the emerging epidemic.针对猴痘I和Ib分支的个性化免疫:应对新出现疫情的策略。
Infect Med (Beijing). 2025 Jan 15;4(1):100166. doi: 10.1016/j.imj.2025.100166. eCollection 2025 Mar.
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Front Pharmacol. 2024 Dec 19;15:1504154. doi: 10.3389/fphar.2024.1504154. eCollection 2024.