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女性型脱发的联合治疗。

Combination therapy in female pattern hair loss.

机构信息

AHRS Fellow, Sadick Dermatology, New York, USA and Senior Resident, Department of Dermatology, Dr. D. Y. Patil Medical College and Hospital, Pune, India.

Sadick Dermatology, New York, USA.

出版信息

J Cosmet Laser Ther. 2023 May 19;25(1-4):1-6. doi: 10.1080/14764172.2023.2222942. Epub 2023 Jun 8.

DOI:10.1080/14764172.2023.2222942
PMID:37289953
Abstract

Patterned hair loss is a common type of non-scarring alopecia, characterized by miniaturization of hair follicles. The etiology of female pattern hair loss (FPHL) is not clearly linked to androgens or other hormones thereby making it a challenging condition to treat. Various treatment modalities, like minoxidil (topical or oral), spironolactone, finasteride, have been tried alone or in combination with variable results. Combination therapy is superior to the monotherapy, since these multiple treatment modalities act by targeting different pathogenetic pathways, making the treatment aggressive and more effective.

摘要

脱发是一种常见的非瘢痕性脱发,其特征是毛囊缩小。女性型脱发 (FPHL) 的病因与雄激素或其他激素没有明确的联系,因此治疗具有挑战性。各种治疗方法,如米诺地尔(局部或口服)、螺内酯、非那雄胺,已被单独或联合使用,但结果各不相同。联合治疗优于单一疗法,因为这些多种治疗方法通过靶向不同的发病途径发挥作用,使治疗更具侵略性和更有效。

相似文献

1
Combination therapy in female pattern hair loss.女性型脱发的联合治疗。
J Cosmet Laser Ther. 2023 May 19;25(1-4):1-6. doi: 10.1080/14764172.2023.2222942. Epub 2023 Jun 8.
2
Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study.0.25%非那雄胺和 3%米诺地尔联合外用治疗女性型脱发的疗效:一项随机、双盲、对照研究。
Am J Clin Dermatol. 2019 Feb;20(1):147-153. doi: 10.1007/s40257-018-0387-0.
3
The efficacy of the combination of topical minoxidil and oral spironolactone compared with the combination of topical minoxidil and oral finasteride in women with androgenic alopecia, female and male hair loss patterns: A blinded randomized clinical trial.与局部外用米诺地尔联合口服非那雄胺相比,局部外用米诺地尔联合口服螺内酯治疗女性雄激素性脱发、女性和男性脱发模式的疗效:一项双盲随机临床试验。
J Cosmet Dermatol. 2024 Feb;23(2):543-551. doi: 10.1111/jocd.15979. Epub 2023 Aug 31.
4
A review of the treatment of male pattern hair loss.男性型脱发的治疗综述。
Expert Opin Pharmacother. 2020 Apr;21(5):603-612. doi: 10.1080/14656566.2020.1721463. Epub 2020 Feb 17.
5
Low level light-minoxidil 5% combination versus either therapeutic modality alone in management of female patterned hair loss: A randomized controlled study.低能量光与5%米诺地尔联合治疗与单独使用任一治疗方式治疗女性型脱发的随机对照研究。
Lasers Surg Med. 2017 Nov;49(9):835-843. doi: 10.1002/lsm.22684. Epub 2017 May 10.
6
Placebo-controlled dose-effect studies with topical minoxidil 2% or 5% in male-patterned hair loss treated with oral finasteride employing an analytical and exhaustive study protocol.采用分析性和详尽的研究方案,对口服非那雄胺治疗的男性型脱发患者进行安慰剂对照剂量效应研究,使用2%或5%的局部用米诺地尔。
Skin Res Technol. 2020 Jul;26(4):542-557. doi: 10.1111/srt.12827. Epub 2020 Jan 19.
7
Efficacy of non-surgical treatments for androgenetic alopecia: a systematic review and network meta-analysis.非手术治疗雄激素性脱发的疗效:一项系统评价和网状Meta分析
J Eur Acad Dermatol Venereol. 2018 Dec;32(12):2112-2125. doi: 10.1111/jdv.15081. Epub 2018 Jul 11.
8
Female-pattern hair loss: therapeutic update.女性型脱发:治疗进展。
An Bras Dermatol. 2023 Jul-Aug;98(4):506-519. doi: 10.1016/j.abd.2022.09.006. Epub 2023 Mar 30.
9
Guidelines for the diagnosis and treatment of male-pattern and female-pattern hair loss, 2017 version.男性型和女性型脱发的诊断和治疗指南,2017 年版。
J Dermatol. 2018 Sep;45(9):1031-1043. doi: 10.1111/1346-8138.14470. Epub 2018 Jun 4.
10
Female pattern hair loss: a pilot study investigating combination therapy with low-dose oral minoxidil and spironolactone.女性型脱发:一项低剂量口服米诺地尔和螺内酯联合治疗的初步研究。
Int J Dermatol. 2018 Jan;57(1):104-109. doi: 10.1111/ijd.13838. Epub 2017 Dec 12.

引用本文的文献

1
The Hormonal Background of Hair Loss in Non-Scarring Alopecias.非瘢痕性脱发的激素背景
Biomedicines. 2024 Feb 24;12(3):513. doi: 10.3390/biomedicines12030513.
2
Dermatologists' Knowledge, Attitude, and Practice Pattern Toward Low-Dose Oral Minoxidil in Hair Loss in Saudi Arabia.沙特阿拉伯皮肤科医生对低剂量口服米诺地尔治疗脱发的知识、态度和实践模式
Clin Cosmet Investig Dermatol. 2024 Mar 15;17:653-662. doi: 10.2147/CCID.S456470. eCollection 2024.