前列腺特异性膜抗原摄取在前列腺混合导管-腺泡性腺癌中的异质性。
Prostate-Specific Membrane Antigen Uptake Heterogeneity in Mixed Ductal-Acinar Adenocarcinoma of the Prostate.
机构信息
From the Department of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia.
Departments of Nuclear Medicine.
出版信息
Clin Nucl Med. 2023 Aug 1;48(8):750-752. doi: 10.1097/RLU.0000000000004742. Epub 2023 Jun 8.
Prostate-specific membrane antigen (PSMA) PET findings of mixed ductal-acinar adenocarcinoma of the prostate are rarely reported. We describe 18 F-PSMA-1007 PET/CT and delayed pelvic 18 F-PSMA-1007 PET/MRI findings in a case of prostatic mixed ductal-acinar adenocarcinoma with multiple lymph node and bone metastases. The primary tumor showed heterogeneous PSMA uptake. The metastases in the right ilium and acetabulum showed intense PSMA uptake, but the pelvic lymph node and left iliac bone metastases showed no significant PSMA uptake. Knowledge of the intraprimary and intermetastatic heterogeneity of PSMA uptake in mixed ductal-acinar adenocarcinoma of the prostate may be helpful for accurate interpretation.
前列腺特异性膜抗原 (PSMA) PET 对前列腺混合性腺泡腺癌的发现很少报道。我们描述了一例前列腺混合性腺泡腺癌的 18 F-PSMA-1007 PET/CT 和延迟盆腔 18 F-PSMA-1007 PET/MRI 结果，该患者伴有多个淋巴结和骨转移。原发肿瘤显示出不均匀的 PSMA 摄取。右髂骨和髋臼的转移灶显示出强烈的 PSMA 摄取，但盆腔淋巴结和左侧髂骨转移灶没有明显的 PSMA 摄取。了解前列腺混合性腺泡腺癌的原发性和转移性摄取的异质性可能有助于准确解释。
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