Castagliuolo P P, Nisini R, Quinti I, Fattorossi A, D'Amelio R
Ann Allergy. 1986 Jul;57(1):68-70.
Five male military recruits were studied for evidence of immunologic deficiencies. Four had recovered recently from a first-episode meningococcal meningitis and one presented with recurrent meningococcemia. A selective decrease in IgG and IgA was found in one of the first-episode patients and a selective IgG2 subclass deficiency in the recurrent case. No complement abnormalities were detected, however, in any of the five cases. These results present further proof of the crucial role of immunoglobulins in the defense against N. meningitidis and they stress the necessity of a through examination of humoral immunity before military career enlistment.
对五名男性新兵进行了免疫缺陷证据的研究。其中四人最近刚从首次发作的脑膜炎球菌性脑膜炎中康复，一人患有复发性脑膜炎球菌血症。在一名首次发作的患者中发现IgG和IgA选择性降低，而复发性病例中存在选择性IgG2亚类缺陷。然而，在这五例病例中均未检测到补体异常。这些结果进一步证明了免疫球蛋白在抵御脑膜炎奈瑟菌中的关键作用，并强调了在军事入伍前全面检查体液免疫的必要性。
