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口服镇痛剂治疗镰状细胞贫血的疼痛危象

Oral analgesia for treatment of painful crisis in sickle cell anemia.

作者信息

Friedman E W, Webber A B, Osborn H H, Schwartz S

出版信息

Ann Emerg Med. 1986 Jul;15(7):787-91. doi: 10.1016/s0196-0644(86)80373-0.

Abstract

A therapeutic plan that emphasized oral narcotic analgesia was instituted for the treatment of painful crisis of sickle cell anemia. Of the 100 adult sickle cell syndrome patients registered at North Central Bronx Hospital, 15 were identified as using the emergency department facilities three or more times per year. This "frequent user" patient population was tracked in their hospital and drug usage patterns during the first full year of the oral protocol and compared to their own patterns during the year prior to the protocol. The patients used the ED at the same rate but their frequency of admissions to the hospital dropped by 75%. The oral program produced a significant fall in the amount of narcotics dispensed in the ED (P less than .01).

摘要

制定了一项强调口服麻醉性镇痛药的治疗方案,用于治疗镰状细胞贫血的疼痛危象。在北中布朗克斯医院登记的100名成年镰状细胞综合征患者中,有15名被确定为每年使用急诊科设施三次或更多次。在口服治疗方案的第一个完整年度,对这群“频繁使用者”的住院情况和用药模式进行了跟踪,并与治疗方案实施前一年他们自己的模式进行了比较。患者使用急诊科的频率不变,但住院频率下降了75%。口服治疗方案使急诊科发放的麻醉药品数量显著减少(P小于0.01)。

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