Department of Mathematics, Quaid-i-Azam University, Islamabad, Pakistan.
School of Engineering, University of Leicester, Leicester, UK.
Sci Prog. 2023 Apr-Jun;106(2):368504231180092. doi: 10.1177/00368504231180092.
This research article interprets the computational fluid dynamics analysis on blood flow inside a symmetric stenosed artery. The current problem models the blood flow inside the left coronary artery as having a symmetric stenosis in the central region. A comprehensive physiological examination of coronary artery disease is numerically evaluated by using the computational fluid dynamics toolbox Open-Field Operation And Manipulation. There are no assumptions of mild stenosis taken into account since the considered stenosis has an exactly measured length, height and position, etc. The blood flow problem is modeled for the non-Newtonian Casson fluid with unsteady, laminar, and incompressible flow assumptions. The underlying problem is solved numerically in its dimensional form. A thorough graphical analysis is provided on the blood flow simulations, pressure profile, velocity line graphs, pressure line graphs, and streamlines for the left coronary artery having a symmetric stenosis formation. The considered artery is divided into three sections, i.e. pre-stenosis, post-stenosis, and stenosis region, and the velocity and pressure line graphs are plotted for these considered regions. The graphical illustrations provide a detailed analysis of how the blood flow is affected inside the left coronary artery due to coronary artery disease. These pre- and post-stenosis velocity line graphs reveal two intriguing results: In the pre-stenosis zone, the velocity increases with increasing axial coordinate length, whereas in the post-stenosis region, the velocity decreases with rising axial coordinate length. It is evident that as the flow moves toward the stenosis region, the flow profile rises; yet, after passing through the stenosis zone, the flow profile begins to fall as the flow moves away from the stenosis region.
这篇研究文章解释了在对称狭窄动脉内血流的计算流体动力学分析。目前的问题模型将左冠状动脉内的血流模拟为在中心区域存在对称狭窄。使用计算流体动力学工具包 Open-Field Operation And Manipulation 对冠状动脉疾病进行了全面的生理评估。由于考虑到的狭窄具有精确测量的长度、高度和位置等，因此没有考虑到轻度狭窄的假设。血流问题是针对非牛顿 Casson 流体建模的，假设为非定常、层流和不可压缩流动。底层问题以其尺寸形式进行数值求解。对具有对称狭窄形成的左冠状动脉血流模拟、压力分布、速度线图、压力线图和流线进行了详细的图形分析。考虑的动脉分为三个部分，即狭窄前、狭窄后和狭窄区，并为这些考虑的区域绘制了速度和压力线图。图形说明详细分析了由于冠状动脉疾病导致左冠状动脉内血流如何受到影响。这些狭窄前和狭窄后速度线图揭示了两个有趣的结果：在狭窄前区，速度随着轴向坐标长度的增加而增加，而在狭窄后区，速度随着轴向坐标长度的增加而减小。显然，随着血流向狭窄区域移动，流型上升；然而，在通过狭窄区域后，随着血流远离狭窄区域，流型开始下降。
