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印度北部无症状2型糖尿病患者冠状动脉疾病的患病率及其与侵入性检查的相关性

Prevalence of Coronary Artery Disease in Asymptomatic type 2 Diabetes Mellitus Patients with Invasive Correlation in North India.

作者信息

Kumar Vinod, Yadav Bharat, Nachankar Amit

机构信息

Department of Medicine, Consultant ITBP Base Hospital Tigri, Delhi, India.

Department of Medicine, Military Hospital Jabalpur, Madhya Pradesh, India.

出版信息

Indian J Endocrinol Metab. 2023 Mar-Apr;27(2):133-139. doi: 10.4103/ijem.ijem_378_22. Epub 2023 Apr 14.

Abstract

INTRODUCTION

Type 2 diabetes mellitus (T2DM) is the risk factor for coronary artery disease (CAD).

MATERIAL AND METHODS

In this study, we assessed the prevalence of CAD in asymptomatic T2DM patients and its correlation with invasive testing in treadmill testing (TMT)-positive cases. A total of 90 patients with asymptomatic T2DM were recruited and subjected to TMT TMT-positive patients were subjected to coronary angiography (CAG).

RESULTS

At baseline, the mean duration of T2DM (years) was 4.87 ± 4.04 with mean levels of HbA1c (%) of 7.96 ± 1.02. TMT was positive in 28 patients (31.1%) for reversible myocardial ischaemia (RMI), and among them, 16 patients consented to CAG, of which 14 required coronary angioplasty and the remaining two (7.1%) had to undergo coronary artery bypass grafting (CABG). The remaining 12 TMT positives (42.9%) were managed medically.

CONCLUSION

To conclude, there is a high prevalence of silent CAD in T2DM. They need regular screening to detect the same and prevent the morbidity and mortality associated with overt CAD. Hence, it is important to screen people with type 2 diabetes, to prevent the morbidity and mortality associated with overt CAD.

摘要

引言

2型糖尿病(T2DM)是冠状动脉疾病(CAD)的危险因素。

材料与方法

在本研究中,我们评估了无症状T2DM患者中CAD的患病率及其与平板运动试验(TMT)阳性病例侵入性检查的相关性。共招募了90例无症状T2DM患者并进行TMT检查。TMT阳性患者接受冠状动脉造影(CAG)检查。

结果

基线时,T2DM的平均病程(年)为4.87±4.04,糖化血红蛋白(HbA1c)平均水平(%)为7.96±1.02。28例患者(31.1%)TMT结果为可逆性心肌缺血(RMI)阳性,其中16例患者同意接受CAG检查,其中14例需要进行冠状动脉成形术,其余2例(7.1%)必须接受冠状动脉旁路移植术(CABG)。其余12例TMT阳性患者(42.9%)接受药物治疗。

结论

总之,T2DM患者中无症状CAD的患病率很高。他们需要定期筛查以发现该病并预防与显性CAD相关的发病率和死亡率。因此,对2型糖尿病患者进行筛查以预防与显性CAD相关的发病率和死亡率很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f821/10245311/89d336c7774c/IJEM-27-133-g001.jpg

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