Clarke Herchel, Nefale Trevor, Mngomezulu Victor
Department of Radiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
SA J Radiol. 2023 May 26;27(1):2634. doi: 10.4102/sajr.v27i1.2634. eCollection 2023.
Worldwide, intracranial aneurysms are associated with a high mortality rate. While endovascular management has proven to be the choice of treatment in selected patients, patient demographics and aneurysm characteristics differ between study populations.
This study aimed to investigate the profile of patients with intracranial aneurysms who underwent endovascular management in the Interventional Neuroradiology Unit at Chris Hani Baragwanath Academic Hospital. Patient demographics, risk factors, indications, aneurysm characteristics and intra-operative complications were studied.
This was a 3-year retrospective study of all adult patients between 01 January 2018 and 31 January 2021. The Chi-square test was used to compare categorical variables.
A total of 77 patients were included in this study. The mean age of the patients was 47 ± 11.6 with a male-to-female ratio of 1:1.8. Hypertension was the most reported risk factor in 27% of patients. There was no statistical correlation between the gender groups according to presentation, multiplicity, aneurysmal size dimensions and locations. According to the presentation, there was statistical significance in ruptured intracranial aneurysms ( = 0.020), neck size dimensions less than 4 mm ( = 0.010), and aneurysms located in the internal cerebral artery (ICA) circulation ( = 0.001).
The study findings support known parameters including females and anterior circulation aneurysm preponderance, and the low complication risk of endovascular management. Interestingly, intracranial aneurysms presented with rupture at smaller size dimensions.
This study provides valuable insights into intracranial aneurysm characteristics and endovascular management efficacy in a resource-limited setting.
在全球范围内,颅内动脉瘤与高死亡率相关。虽然血管内治疗已被证明是特定患者的治疗选择,但不同研究人群的患者人口统计学特征和动脉瘤特征存在差异。
本研究旨在调查在克里斯·哈尼·巴拉格瓦纳特学术医院介入神经放射科接受血管内治疗的颅内动脉瘤患者的情况。研究了患者的人口统计学特征、危险因素、适应症、动脉瘤特征和术中并发症。
这是一项对2018年1月1日至2021年1月31日期间所有成年患者进行的为期3年的回顾性研究。采用卡方检验比较分类变量。
本研究共纳入77例患者。患者的平均年龄为47±11.6岁,男女比例为1:1.8。27%的患者报告高血压是最常见的危险因素。根据临床表现、多发性、动脉瘤大小和位置,性别组之间无统计学相关性。根据临床表现,颅内动脉瘤破裂(P = 0.020)、颈部尺寸小于4mm(P = 0.010)和位于大脑中动脉(ICA)循环的动脉瘤(P = 0.001)具有统计学意义。
研究结果支持已知参数,包括女性和前循环动脉瘤占优势,以及血管内治疗的低并发症风险。有趣的是,颅内动脉瘤在较小尺寸时就出现破裂。
本研究为资源有限环境下的颅内动脉瘤特征和血管内治疗疗效提供了有价值的见解。