蜱虫及蜱传病毒性疾病的地理分布与发病机制。
Geographical distribution and pathogenesis of ticks and tick-borne viral diseases.
作者信息
Shah Taif, Li Qian, Wang Binghui, Baloch Zulqarnain, Xia Xueshan
机构信息
Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, China.
Provincial Center for Molecular Medicine, Kunming, China.
出版信息
Front Microbiol. 2023 May 24;14:1185829. doi: 10.3389/fmicb.2023.1185829. eCollection 2023.
Ticks are obligatory hematophagous arthropods that harbor and transmit infectious pathogens to humans and animals. Tick species belonging to , , , and genera may transmit certain viruses such as Bourbon virus (BRBV), Dhori virus (DHOV), Powassan virus (POWV), Omsk hemorrhagic fever virus (OHFV), Colorado tick fever virus (CTFV), Crimean-Congo hemorrhagic fever virus (CCHFV), Heartland virus (HRTV), Kyasanur forest disease virus (KFDV), etc. that affect humans and certain wildlife. The tick vectors may become infected through feeding on viraemic hosts before transmitting the pathogen to humans and animals. Therefore, it is vital to understand the eco-epidemiology of tick-borne viruses and their pathogenesis to optimize preventive measures. Thus this review summarizes knowledge on some medically important ticks and tick-borne viruses, including BRBV, POWV, OHFV, CTFV, CCHFV, HRTV, and KFDV. Further, we discuss these viruses' epidemiology, pathogenesis, and disease manifestations during infection.
蜱是专性吸血节肢动物，可携带感染性病原体并将其传播给人类和动物。属于 、 、 和 属的蜱种可能传播某些病毒，如波旁病毒（BRBV）、多里病毒（DHOV）、波瓦桑病毒（POWV）、鄂木斯克出血热病毒（OHFV）、科罗拉多蜱传热病毒（CTFV）、克里米亚-刚果出血热病毒（CCHFV）、哈特兰病毒（HRTV）、基萨努尔森林病病毒（KFDV）等，这些病毒会影响人类和某些野生动物。蜱传播媒介在将病原体传播给人类和动物之前，可能通过吸食病毒血症宿主而被感染。因此，了解蜱传病毒的生态流行病学及其发病机制对于优化预防措施至关重要。因此，本综述总结了一些具有医学重要性的蜱和蜱传病毒的相关知识，包括BRBV、POWV、OHFV、CTFV、CCHFV、HRTV和KFDV。此外，我们还讨论了这些病毒在感染期间的流行病学、发病机制和疾病表现。
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