健康志愿者中伦氨西林（KBT-1585）的药代动力学研究。
Pharmacokinetic study of lenampicillin (KBT-1585) in healthy volunteers.
作者信息
Saito A, Nakashima M
出版信息
Antimicrob Agents Chemother. 1986 May;29(5):948-50. doi: 10.1128/AAC.29.5.948.
Abstract
The pharmacokinetic properties of lenampicillin (KBT-1585), a new ampicillin ester, were investigated in 41 healthy volunteers. The maximum concentration of ampicillin in serum after oral administration of 400 mg of lenampicillin was 6.5 micrograms/ml at 0.70 h, and that after a equimolar dosage of ampicillin was 2.9 micrograms/ml at 0.87 h.
摘要
在41名健康志愿者中研究了新型氨苄西林酯仑氨西林（KBT-1585）的药代动力学特性。口服400mg仑氨西林后，血清中氨苄西林的最大浓度在0.70小时时为6.5微克/毫升，而给予等摩尔剂量的氨苄西林后，在0.87小时时为2.9微克/毫升。
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