Programa de Pós-Graduação em Ciências Farmacêuticas (CiPharma), Escola de Farmácia, Universidade Federal de Ouro Preto, Ouro Preto, Brazil.
Departamento de Análises Clínicas (DEACL), Escola de Farmácia, Universidade Federal de Ouro Preto, Ouro Preto, Brazil.
J Behav Med. 2024 Feb;47(1):94-101. doi: 10.1007/s10865-023-00420-y. Epub 2023 Jun 9.
To evaluate the effect of yoga on the frequency of MetS and its impact on cardiovascular risk markers in climacteric women. We recruited 84 sedentary women between 40 and 65 years diagnosed with MetS. Participants were randomly assigned to a 24-week yoga intervention or control group. We evaluated the frequency of MetS and changes in the individual components of MetS at baseline and after 24 weeks. We also assessed the impact of yoga practices on cardiovascular risk through the following markers: High-sensitivity C-reactive Protein (hs-CRP), Lipid Accumulation Product (LAP), Visceral Adiposity Index (VAI), and Atherogenic Index of Plasma (AIP). The frequency of MetS reduced significantly after 24 weeks of yoga practice (- 34.1%; p < 0.001). Statistical analysis showed that the frequency of MetS was significantly lower in the yoga group (65.9%; n = 27) than in the control group (93.0%; n = 40) after 24 weeks (p = 0.002). Regarding the individual components of MetS, yoga practitioners had statistically lower waist circumference, systolic blood pressure, triglycerides, HDLc, and glucose serum concentrations than the control group after 24 weeks. Yoga practitioners also had a significant decrease in hs-CRP serum concentrations (3.27 ± 2.95 mg/L vs. 2.52 ± 2.14 mg/L; p = 0.040) and a lower frequency of moderate or high cardiovascular risk (48.8% vs. 34.1%; p = 0.001) after 24 weeks of practice. The yoga group had LAP values significantly lower than the control group after the intervention period (55.8 ± 38.04 vs. 73.9 ± 40.7; p = 0.039). Yoga practice demonstrated to be an effective therapeutic to manage MetS and reduce cardiovascular risk in climacteric women.
评估瑜伽对代谢综合征（Metabolic Syndrome，MetS）频率的影响及其对绝经期女性心血管风险标志物的影响。我们招募了 84 名年龄在 40 至 65 岁之间、被诊断为 MetS 的久坐不动的女性。参与者被随机分配到 24 周的瑜伽干预组或对照组。我们评估了基线时和 24 周后 MetS 的频率以及 MetS 各组成部分的变化。我们还通过以下标志物评估瑜伽练习对心血管风险的影响：高敏 C 反应蛋白（hs-CRP）、脂质蓄积产物（LAP）、内脏脂肪指数（VAI）和血浆致动脉粥样硬化指数（AIP）。经过 24 周的瑜伽练习，MetS 的频率显著降低（-34.1%；p<0.001）。统计分析显示，在 24 周后，瑜伽组的 MetS 频率明显低于对照组（瑜伽组 65.9%，n=27；对照组 93.0%，n=40）（p=0.002）。关于 MetS 的各个组成部分，经过 24 周的瑜伽练习，瑜伽练习者的腰围、收缩压、甘油三酯、HDLc 和血糖血清浓度均显著低于对照组。瑜伽练习者在 24 周后 hs-CRP 血清浓度也有显著下降（3.27±2.95 mg/L 比 2.52±2.14 mg/L；p=0.040），且中高危心血管风险的发生率较低（48.8%比 34.1%；p=0.001）。干预后，瑜伽组的 LAP 值明显低于对照组（55.8±38.04 比 73.9±40.7；p=0.039）。瑜伽练习被证明是一种有效的治疗方法，可以管理绝经期女性的 MetS 并降低心血管风险。
