Suppr超能文献

钝性胸部创伤伴肋骨骨折患者肺部并发症预测的新型列线图:一项回顾性队列研究。

Novel nomogram for predicting pulmonary complications in patients with blunt chest trauma with rib fractures: a retrospective cohort study.

机构信息

Department of Thoracic and Cardiovascular Surgery, Chungbuk National University Hospital, Cheongju, 28644, South Korea.

Department of Trauma Surgery, Chungbuk National University Hospital, Cheongju, 28644, South Korea.

出版信息

Sci Rep. 2023 Jun 9;13(1):9448. doi: 10.1038/s41598-023-36679-z.

Abstract

The direct consequences of chest trauma may cause adverse outcomes. Therefore, the early detection of high-risk patients and appropriate interventions can improve patient outcomes. This study aimed to investigate the risk factor for overall pulmonary complications in patients with blunt traumatic rib fractures. Prospectively recorded data of patients with blunt chest trauma in a level 1 trauma center between January 2019 and October 2022 were retrospectively analyzed. The primary outcomes were one or more pulmonary complications. To minimize the overfitting of the prediction model, we used the least absolute shrinkage and selection operator (LASSO) logistic regression. We input selected features using LASSO regression into the multivariable logistic regression model (MLR). We also constructed a nomogram to calculate approximate individual probability. Altogether, 542 patients were included. The LASSO regression model identified age, injury severity score (ISS), and flail motion of the chest wall as significant risk factors. In the MLR analysis, age (adjusted OR [aOR] 1.06; 95% confidence interval [CI] 1.03-1.08; p < 0.001), ISS (aOR 1.10; 95% CI 1.05-1.16; p < 0.001), and flail motion (aOR 8.82; 95% CI 4.13-18.83; p < 0.001) were significant. An MLR-based nomogram predicted the individual risk, and the area under the receiver operating characteristic curve was 0.826. We suggest a novel nomogram with good performance for predicting adverse pulmonary outcomes. The flail motion of the chest wall may be the most significant risk factor for pulmonary complications.

摘要

胸部创伤的直接后果可能导致不良后果。因此,早期发现高危患者并进行适当的干预可以改善患者的预后。本研究旨在探讨钝性创伤性肋骨骨折患者总体肺部并发症的危险因素。回顾性分析了 2019 年 1 月至 2022 年 10 月期间,1 级创伤中心的钝性胸部创伤患者的前瞻性记录数据。主要结局是一个或多个肺部并发症。为了最小化预测模型的过度拟合,我们使用了最小绝对收缩和选择算子(LASSO)逻辑回归。我们使用 LASSO 回归将选定的特征输入多变量逻辑回归模型(MLR)。我们还构建了一个列线图来计算近似个体概率。共纳入 542 例患者。LASSO 回归模型确定年龄、损伤严重度评分(ISS)和胸壁连枷运动为显著危险因素。在 MLR 分析中,年龄(调整后的 OR [aOR] 1.06;95%置信区间 [CI] 1.03-1.08;p<0.001)、ISS(aOR 1.10;95% CI 1.05-1.16;p<0.001)和连枷运动(aOR 8.82;95% CI 4.13-18.83;p<0.001)均有显著意义。基于 MLR 的列线图预测了个体风险,接受者操作特征曲线下的面积为 0.826。我们提出了一种基于 MLR 的新型列线图,具有良好的预测不良肺部结局的性能。胸壁连枷运动可能是肺部并发症的最重要危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e425/10256745/d7f2e3e744fb/41598_2023_36679_Fig1_HTML.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验