Physiotherapy and Occupational Therapy Research Center, Directorate of Research and Education, University Hospital Zurich, Zurich, Switzerland.
Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.
Sci Rep. 2023 Jun 9;13(1):9450. doi: 10.1038/s41598-023-36655-7.
A feasible, inexpensive, rapid, and easy-to-use method to measure vestibular vertical movement perception is needed to assess the sacculus-mediated low-frequency otolith function of dizzy patients. To evaluate the feasibility of reaction time assessment in response to vertical motion induced by an elevator in healthy young individuals. We recorded linear acceleration/deceleration reaction times (LA-RT/LD-RT) of 20 healthy (13 female) subjects (mean age: 22 years ± 1 SD) as a measure of vertical vestibular motion perception. LA-RT/LD-RT were defined as the time elapsed from the start of elevator acceleration or deceleration to the time at which subjects in a sitting position indicated perceiving a change in velocity by pushing a button with their thumb. The light reaction time was measured as a reference. All 20 subjects tolerated the assessment with repeated elevator rides and reported no adverse events. Over all experiments, one upward and four downward rides had to be excluded for technical reasons (2.5%). The fraction of premature button presses varied among the four conditions, possibly related to elevator vibration (upward rides: LA-RT-up 66%, LD-RT-up 0%; downward rides: LA-RT-down 12%, LD-RT-down 4%). Thus LD-RT-up yielded the most robust results. The reaction time to earth-vertical deceleration elicited by an elevator provides a consistent indicator of linear vestibular motion perception in healthy humans. The testing procedure is inexpensive and easy to use. Deceleration on upward rides yielded the most robust measurements.
需要一种可行、廉价、快速且易于使用的方法来测量前庭垂直运动感知，以评估 dizzy 患者的囊介导低频耳石功能。评估反应时间评估在健康年轻个体中对电梯引起的垂直运动的可行性。我们记录了 20 名健康（13 名女性）受试者（平均年龄：22 岁±1 标准差）的线性加速度/减速反应时间（LA-RT/LD-RT），作为垂直前庭运动感知的衡量标准。LA-RT/LD-RT 定义为从电梯加速或减速开始到受试者坐在座位上用拇指按下按钮以感知速度变化的时间。测量光反应时间作为参考。所有 20 名受试者均耐受重复乘坐电梯的评估，且无不良反应报告。在所有实验中，由于技术原因（2.5%），必须排除一次向上和四次向下的电梯行程。四种条件下的提前按按钮的比例不同，可能与电梯振动有关（向上行程：LA-RT-up 66%，LD-RT-up 0%；向下行程：LA-RT-down 12%，LD-RT-down 4%）。因此，LD-RT-up 产生了最可靠的结果。电梯引起的地球垂直减速的反应时间为健康人类提供了线性前庭运动感知的一致指标。测试过程廉价且易于使用。向上行程的减速产生了最可靠的测量结果。
