Akmal Haad, Hardalaç Fırat, Ayturan Kubilay
Department of Electrical and Electronics Engineering, Gazi University, Ankara 06570, Turkey.
Diagnostics (Basel). 2023 Jun 1;13(11):1931. doi: 10.3390/diagnostics13111931.
Cardiotocography (CTG), which measures the fetal heart rate (FHR) and maternal uterine contractions (UC) simultaneously, is used for monitoring fetal well-being during delivery or antenatally at the third trimester. Baseline FHR and its response to uterine contractions can be used to diagnose fetal distress, which may necessitate therapeutic intervention. In this study, a machine learning model based on feature extraction (autoencoder), feature selection (recursive feature elimination), and Bayesian optimization, was proposed to diagnose and classify the different conditions of fetuses (Normal, Suspect, Pathologic) along with the CTG morphological patterns. The model was evaluated on a publicly available CTG dataset. This research also addressed the imbalance nature of the CTG dataset. The proposed model has a potential application as a decision support tool to manage pregnancies. The proposed model resulted in good performance analysis metrics. Using this model with Random Forest resulted in a model accuracy of 96.62% for fetal status classification and 94.96% for CTG morphological pattern classification. In rational terms, the model was able to accurately predict 98% Suspect cases and 98.6% Pathologic cases in the dataset. The combination of predicting and classifying fetal status as well as the CTG morphological patterns shows potential in monitoring high-risk pregnancies.
胎心宫缩图(CTG)可同时测量胎儿心率(FHR)和母体子宫收缩(UC),用于分娩期间或孕晚期产前监测胎儿健康状况。基线FHR及其对子宫收缩的反应可用于诊断胎儿窘迫,这可能需要进行治疗干预。在本研究中,提出了一种基于特征提取(自动编码器)、特征选择(递归特征消除)和贝叶斯优化的机器学习模型,用于对胎儿的不同状况(正常、可疑、病理)以及CTG形态模式进行诊断和分类。该模型在一个公开可用的CTG数据集上进行了评估。本研究还探讨了CTG数据集的不均衡特性。所提出的模型具有作为管理妊娠的决策支持工具的潜在应用价值。所提出的模型产生了良好的性能分析指标。将该模型与随机森林结合使用,胎儿状态分类的模型准确率为96.62%,CTG形态模式分类的准确率为94.96%。从合理的角度来看,该模型能够准确预测数据集中98%的可疑病例和98.6%的病理病例。预测和分类胎儿状态以及CTG形态模式的结合在监测高危妊娠方面显示出潜力。