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基于产程两个阶段的胎心监护图的胎儿健康分类——一种基于软计算的方法

Fetal Health Classification from Cardiotocograph for Both Stages of Labor-A Soft-Computing-Based Approach.

作者信息

Das Sahana, Mukherjee Himadri, Roy Kaushik, Saha Chanchal Kumar

机构信息

School of Computer Science, Swami Vivekananda University, Kolkata 700121, India.

Department of Computer Science, West Bengal State University, Kolkata 700126, India.

出版信息

Diagnostics (Basel). 2023 Feb 23;13(5):858. doi: 10.3390/diagnostics13050858.

Abstract

To date, cardiotocography (CTG) is the only non-invasive and cost-effective tool available for continuous monitoring of the fetal health. In spite of a marked growth in the automation of the CTG analysis, it still remains a challenging signal processing task. Complex and dynamic patterns of fetal heart are poorly interpreted. Particularly, the precise interpretation of the suspected cases is fairly low by both visual and automated methods. Also, the first and second stage of labor produce very different fetal heart rate (FHR) dynamics. Thus, a robust classification model takes both stages into consideration separately. In this work, the authors propose a machine-learning-based model, which was applied separately to both the stages of labor, using standard classifiers such as SVM, random forest (RF), multi-layer perceptron (MLP), and bagging to classify the CTG. The outcome was validated using the model performance measure, combined performance measure, and the ROC-AUC. Though AUC-ROC was sufficiently high for all the classifiers, the other parameters established a better performance by SVM and RF. For suspicious cases the accuracies of SVM and RF were 97.4% and 98%, respectively, whereas sensitivity was 96.4% and specificity was 98% approximately. In the second stage of labor the accuracies were 90.6% and 89.3% for SVM and RF, respectively. Limits of agreement for 95% between the manual annotation and the outcome of SVM and RF were (-0.05 to 0.01) and (-0.03 to 0.02). Henceforth, the proposed classification model is efficient and can be integrated into the automated decision support system.

摘要

迄今为止,胎心监护(CTG)是唯一可用于持续监测胎儿健康的非侵入性且经济高效的工具。尽管CTG分析的自动化程度有了显著提高,但它仍然是一项具有挑战性的信号处理任务。胎儿心脏的复杂动态模式难以解读。特别是,无论是视觉方法还是自动化方法,对疑似病例的精确解读都相当低。此外,分娩的第一阶段和第二阶段会产生非常不同的胎儿心率(FHR)动态。因此,一个强大的分类模型需要分别考虑这两个阶段。在这项工作中,作者提出了一种基于机器学习的模型,该模型分别应用于分娩的两个阶段,使用支持向量机(SVM)、随机森林(RF)、多层感知器(MLP)等标准分类器对CTG进行分类。使用模型性能度量、综合性能度量和ROC-AUC对结果进行了验证。尽管所有分类器的AUC-ROC都足够高,但其他参数表明SVM和RF的性能更好。对于可疑病例,SVM和RF的准确率分别为97.4%和98%,而敏感性约为96.4%,特异性为98%。在分娩的第二阶段,SVM和RF的准确率分别为90.6%和89.3%。手动标注与SVM和RF结果之间95%的一致性界限分别为(-0.05至0.01)和(-0.03至0.02)。因此,所提出的分类模型是有效的,可以集成到自动化决策支持系统中。

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