Correyero-León Marta, Llamas-Ramos Rocío, Calvo-Rodrigo Javier, Alvarado-Omenat Jorge Juan, Llamas-Ramos Inés
CEIP Simón de Colonia, Calle Padre Janáriz, 11, 09400 Aranda de Duero, Spain.
Department of Nursing and Physiotherapy, Faculty of Nursing and Physiotherapy, Universidad de Salamanca, Avda, Donantes de Sangre s/n, 37007 Salamanca, Spain.
Healthcare (Basel). 2023 Jun 2;11(11):1633. doi: 10.3390/healthcare11111633.
Primary dysmenorrhea (PD) is a painful menstruation that can persist for the duration of a woman's fertile life. Non-steroidal anti-inflammatory drugs, hormonal therapy, physiotherapy techniques, etc., are the main treatments. The main objective of this study is to evaluate the effectiveness of transcutaneous posterior tibial nerve stimulation (TTNS) in PD patients. The study will consist of a single-blind randomized clinical trial, parallel-assigned with two arms. Women with PD (18-43 years) with regular menstrual cycles and at least 4 points in VAS will be randomly divided into experimental (TTNS) and placebo (simulated stimulation) groups during 12 treatment sessions (1 session/week) and several follow-ups: monthly during treatment and 1, 3 and 6 months after. Maximum and mean pain intensity, pain duration, pain severity, number of anti-inflammatory drugs, quality of life, sleep quality, overall improvement, treatment satisfaction and secondary effects will be measured once a month every 6 months and at 3 and 6 months. The Student's -test for independent samples or the Mann-Whitney U test will be used. The literature shows effective physiotherapeutic techniques for PD in the short term, which do not act on causes and have limitations. The TTNS technique can be used in transcutaneous and percutaneous modalities, with similar effectiveness, but the transcutaneous causes less discomfort. TTNS modulates pain, and long-term benefits could be achieved at low cost and without patient discomfort.
原发性痛经（PD）是一种疼痛性月经，可在女性的生育期持续存在。非甾体类抗炎药、激素疗法、物理治疗技术等是主要治疗方法。本研究的主要目的是评估经皮胫后神经刺激（TTNS）对PD患者的有效性。该研究将包括一项单盲随机临床试验，平行分为两组。月经周期规律、视觉模拟评分（VAS）至少4分的18至43岁PD女性将在12次治疗疗程（每周1次）及多次随访期间随机分为实验组（TTNS）和安慰剂组（模拟刺激）：治疗期间每月随访，治疗后1、3和6个月随访。每6个月、3个月和6个月每月测量一次最大和平均疼痛强度、疼痛持续时间、疼痛严重程度、抗炎药使用次数、生活质量、睡眠质量、总体改善情况、治疗满意度和副作用。将使用独立样本t检验或曼-惠特尼U检验。文献表明，现有的物理治疗技术对PD的短期治疗有效，但这些技术并非针对病因，且存在局限性。TTNS技术可采用经皮和皮下两种方式，效果相似，但经皮方式引起的不适较少。TTNS可调节疼痛，且能以低成本实现长期益处，同时不会给患者带来不适。
