Key Laboratory for Molecular Enzymology & Engineering of the Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China.
Nutrients. 2023 May 23;15(11):2434. doi: 10.3390/nu15112434.
The active components of ginseng, such as ginsenosides and polysaccharides, have high therapeutic value in treating cancer, decreasing obesity, and enhancing immunity. However, simple primary ginseng treatment cannot maximize this medicinal potential. Therefore, in this study, was co-fermented with multi-enzyme-coupling probiotics to obtain a fermentation broth with higher levels of ginsenosides, polysaccharides, and probiotics. When compared to other treatment methods for cyclophosphamide-induced immunosuppression in mice, the results reveal that the fermentation broth treated with multi-enzyme-coupling probiotics could significantly improve the immune function of immunosuppressive mice and restore intestinal flora stability. Overall, this processing method will provide a novel strategy for promoting the application of ginseng and the relief of immunosuppression.
人参中的活性成分，如人参皂苷和多糖，在治疗癌症、减肥和增强免疫力方面具有很高的治疗价值。然而，单纯的初级人参治疗并不能最大限度地发挥这种药用潜力。因此，在本研究中，人参被与多酶偶联益生菌共发酵，以获得一种具有更高水平的人参皂苷、多糖和益生菌的发酵液。与其他用于治疗环磷酰胺诱导的小鼠免疫抑制的方法相比，结果表明，经多酶偶联益生菌发酵的人参发酵液可以显著改善免疫抑制小鼠的免疫功能，并恢复肠道菌群的稳定性。总的来说，这种加工方法将为人参的应用和免疫抑制的缓解提供一种新的策略。
