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《1 型糖尿病青少年和年轻成人健康体重的饮食和身体活动概述:ACT1ON 联盟的经验教训》。

An Overview of Diet and Physical Activity for Healthy Weight in Adolescents and Young Adults with Type 1 Diabetes: Lessons Learned from the ACT1ON Consortium.

机构信息

Division of Endocrinology, Department of Pediatrics, School of Medicine, Stanford University, Stanford, CA 94304, USA.

AdventHealth, Translational Research Institute, Orlando, FL 32804, USA.

出版信息

Nutrients. 2023 May 27;15(11):2500. doi: 10.3390/nu15112500.

Abstract

The prevalence of overweight and obesity in young people with type 1 diabetes (T1D) now parallels that of the general population. Excess adiposity increases the risk of cardiovascular disease, which is already elevated up to 10-fold in T1D, underscoring a compelling need to address weight management as part of routine T1D care. Sustainable weight management requires both diet and physical activity (PA). Diet and PA approaches must be optimized towards the underlying metabolic and behavioral challenges unique to T1D to support glycemic control throughout the day. Diet strategies for people with T1D need to take into consideration glycemic management, metabolic status, clinical goals, personal preferences, and sociocultural considerations. A major barrier to weight management in this high-risk population is the challenge of integrating regular PA with day-to-day management of T1D. Specifically, exercise poses a substantial challenge due to the increased risk of hypoglycemia and/or hyperglycemia. Indeed, about two-thirds of individuals with T1D do not engage in the recommended amount of PA. Hypoglycemia presents a serious health risk, yet prevention and treatment often necessitates the consumption of additional calories, which may prohibit weight loss over time. Exercising safely is a concern and challenge with weight management and maintaining cardiometabolic health for individuals living with T1D and many healthcare professionals. Thus, a tremendous opportunity exists to improve exercise participation and cardiometabolic outcomes in this population. This article will review dietary strategies, the role of combined PA and diet for weight management, current resources for PA and glucose management, barriers to PA adherence in adults with T1D, as well as findings and lessons learned from the Advancing Care for Type 1 Diabetes and Obesity Network (ACT1ON).

摘要

如今,青少年 1 型糖尿病(T1D)患者超重和肥胖的患病率与普通人群相当。肥胖会增加心血管疾病的风险,而 T1D 患者的心血管疾病风险已经增加了 10 倍,这突显出迫切需要将体重管理作为 T1D 常规护理的一部分。可持续的体重管理需要饮食和身体活动(PA)。饮食和 PA 方法必须针对 T1D 特有的潜在代谢和行为挑战进行优化,以支持全天的血糖控制。T1D 患者的饮食策略需要考虑血糖管理、代谢状况、临床目标、个人喜好和社会文化因素。在这个高风险人群中,体重管理的一个主要障碍是将定期 PA 与 T1D 的日常管理相结合的挑战。具体来说,由于低血糖和/或高血糖的风险增加,运动带来了实质性的挑战。事实上,大约三分之二的 T1D 患者没有进行推荐量的 PA。低血糖会带来严重的健康风险,但预防和治疗通常需要额外的卡路里摄入,这可能会随着时间的推移阻止体重减轻。安全运动是 T1D 患者管理体重和维持心血管代谢健康的关注和挑战,许多医疗保健专业人员也存在这个问题。因此,为了改善该人群的运动参与度和心血管代谢结果,存在巨大的机会。本文将回顾饮食策略、PA 和饮食联合管理体重的作用、目前用于 PA 和血糖管理的资源、T1D 成人坚持 PA 的障碍,以及推进 1 型糖尿病和肥胖网络(ACT1ON)的研究结果和经验教训。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fb3/10255747/a91acb5052f8/nutrients-15-02500-g001.jpg

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