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意外硬脊膜穿刺后硬膜外血贴治疗:叙事性综述。

Accidental dural puncture during epidural blood patch: a narrative review.

机构信息

Glasgow Royal Infirmary/Princess Royal Maternity Hospital, Glasgow, UK.

出版信息

Int J Obstet Anesth. 2023 Aug;55:103900. doi: 10.1016/j.ijoa.2023.103900. Epub 2023 May 29.

Abstract

Whilst performing an epidural blood patch (EBP) to treat post dural-puncture headache following accidental or intentional dural puncture, the risk of a subsequent accidental dural puncture (ADP) is commonly quoted as 1%. However, a recent review reported only three documented cases. It seems likely that this complication is more common than is acknowledged, yet there is a paucity of literature and an absence of any guidance as to how to proceed in practice. This review addresses three unanswered questions regarding ADP during EBP: what is the incidence; what are the immediate clinical consequences; and what is the optimal clinical management? The incidence may reasonably be estimated to be 0.5-1%. Even on large units, this complication will not be experienced by every consultant anaesthetist during their career. It is likely to occur 20-30 times per year in the United Kingdom, and in greater numbers in those countries with higher epidural rates. Immediately re-attempting an EBP at a different level may be a reasonable management approach which has high efficacy, and is without clear evidence of significant harm. However, the limited evidence means that the risks are poorly characterised, and more data may lead to alternative conclusions. There is uncertainty amongst obstetric anaesthetists about how to manage ADP during EBP. More data and pragmatic guidance, which evolves with further evidence, will ensure optimal care for patients suffering this compound iatrogenic complication.

摘要

在进行硬膜外血补丁(EBP)以治疗意外或故意刺破硬脑膜后出现的硬膜穿刺后头痛时,后续发生意外硬脑膜穿刺(ADP)的风险通常被引用为 1%。然而,最近的一项综述仅报道了三例有记录的病例。这种并发症似乎比公认的更为常见,但文献匮乏,也缺乏关于如何在实践中处理的指导。本文针对 EBP 期间 ADP 提出了三个未解答的问题:发生率是多少;立即出现的临床后果是什么;最佳的临床管理方法是什么?发生率可能合理地估计为 0.5-1%。即使在大单位,这种并发症也不会在每位顾问麻醉师的职业生涯中都经历到。在英国,每年可能发生 20-30 次,在硬膜外使用率较高的国家,发生的次数更多。在不同水平重新立即尝试 EBP 可能是一种合理的管理方法,其疗效高,且没有明显的严重伤害的证据。然而,有限的证据意味着风险特征描述不充分,更多的数据可能会得出不同的结论。产科麻醉师对如何在 EBP 期间处理 ADP 存在不确定性。更多的数据和实用指南,随着进一步的证据而不断发展,将确保为遭受这种复合医源性并发症的患者提供最佳护理。

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