Chau Anthony, Preston Roanne, Wieczorek Paul M, McKeen Dolores M, Chow Lorraine, Edwards Wesley, Zaphiratos Valerie
Department of Anesthesiology, Pharmacology & Therapeutics, The University of British Columbia, Vancouver, BC, Canada.
Department of Anesthesia, BC Women's Hospital, Vancouver, BC, Canada.
Can J Anaesth. 2025 Jun 17. doi: 10.1007/s12630-025-02986-4.
This Special Article aims to synthesize the results of a live audience poll and practice tips from Canadian obstetric anesthesiology experts during a panel session at the Canadian Anesthesiologists' Society 2024 Annual Meeting (Victoria, BC, Canada). We explored six hypothetical case scenarios, each representing a clinically plausible situation that lack a definitive management approach. These scenarios highlight areas where no consensus exists and no single "correct" solution has been established.
We gathered live poll data about six case scenarios from participants who attended the session and chose to submit a response. The expert panel provided decision analysis of each case.
The literature and expert panel suggest that 0.5% isobaric bupivacaine and 0.5% hyperbaric ropivacaine may be appropriate alternatives during shortages of 0.75% hyperbaric bupivacaine. Both combined spinal epidural and standard epidural techniques are effective first choices for rescuing a failed single-shot spinal anesthesia during elective Cesarean delivery. A decision aid may be helpful when converting an epidural for surgical anesthesia. Epidural dexmedetomidine has been used off-label in some centres to enhance the quality of labour analgesia. Nevertheless, owing to limited data in the literature, its routine use for labour analgesia or Cesarean delivery is not currently recommended. In cases of febrile labouring patients, the expert panel advocates initiating antibiotics before epidural placement as a prudent precaution despite the lack of robust contemporary evidence. An obstetric patient with thrombocytopenia may generally undergo neuraxial techniques if the platelet count exceeds 70 × 10·L. The risks and benefits should be carefully considered when the platelet count is between 50 × 10·L and 69 × 10·L, taking into account potential changes in platelet quality due to conditions such as hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome. If an accidental dural puncture occurs during an epidural blood patch procedure, a cautious approach would involve abandoning the procedure and reattempting after 24 hr to minimize the risk of blood translocation leading to arachnoiditis. Conversely, a pragmatic approach would involve immediately reattempting the procedure at another level, although there is no consensus on the most appropriate course of action.
The range of participant responses highlighted various clinical challenges in obstetric anesthesia where evidence is still limited or inconclusive. Three experts in obstetric anesthesia shared their insights, detailing their decision-making processes and how they would approach each case scenario. They also provided key references, offering valuable take-home messages for anesthesiologists practicing obstetric anesthesia.
本专题文章旨在综合现场观众投票结果以及加拿大麻醉医师协会2024年年会(加拿大不列颠哥伦比亚省维多利亚市)小组讨论期间加拿大产科麻醉专家提供的实践技巧。我们探讨了六种假设病例情景,每种情景代表一种临床上似是而非但缺乏明确管理方法的情况。这些情景突出了尚无共识且未确立单一“正确”解决方案的领域。
我们收集了参加该会议并选择提交回复的参与者关于六种病例情景的现场投票数据。专家小组对每个病例进行了决策分析。
文献和专家小组表明,在0.75%重比重布比卡因短缺期间,0.5%等比重布比卡因和0.5%轻比重罗哌卡因可能是合适的替代药物。在择期剖宫产手术中,联合腰麻硬膜外麻醉和标准硬膜外麻醉技术都是挽救单次腰麻失败的有效首选方法。在将硬膜外麻醉转换为手术麻醉时,决策辅助工具可能会有所帮助。硬膜外右美托咪定在一些中心已被超说明书使用以提高分娩镇痛质量。然而,由于文献中的数据有限,目前不建议将其常规用于分娩镇痛或剖宫产。对于发热的临产患者,尽管缺乏有力的当代证据,但专家小组主张在放置硬膜外导管前预防性使用抗生素。血小板减少的产科患者,如果血小板计数超过70×10⁹/L,一般可接受神经轴索阻滞技术。当血小板计数在50×10⁹/L至69×10⁹/L之间时,应仔细考虑风险和益处,同时考虑溶血、肝酶升高和血小板减少(HELLP)综合征等情况导致的血小板质量潜在变化。如果在硬膜外血贴操作过程中意外发生硬膜穿刺,谨慎的做法是放弃该操作,并在24小时后重新尝试,以尽量降低血液移位导致蛛网膜炎的风险。相反,务实的做法是立即在另一个节段重新尝试该操作,尽管对于最合适的行动方案尚无共识。
参与者的回答范围突出了产科麻醉中各种临床挑战,在这些方面证据仍然有限或不确定。三位产科麻醉专家分享了他们的见解,详细阐述了他们的决策过程以及他们将如何处理每种病例情景。他们还提供了关键参考文献,并为从事产科麻醉的麻醉医师提供了宝贵的实用信息。