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变应性支气管肺曲霉病:一例报告

Allergic Bronchopulmonary Aspergillosis: A Case Report.

作者信息

Bouali Siham, Legssyer Imane, Thouil Afaf, Kouismi Hatim

机构信息

Department of Respiratory Diseases, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.

Department of Respiratory Diseases, Mohammed VI University Hospital, Oujda, MAR.

出版信息

Cureus. 2023 May 9;15(5):e38778. doi: 10.7759/cureus.38778. eCollection 2023 May.

Abstract

Allergic bronchopulmonary aspergillosis (ABPA) is an underdiagnosed lung condition in patients with asthma and cystic fibrosis. Its clinical and diagnostic manifestations result from an allergic response to multiple antigens expressed by , which colonize the bronchial mucus. This report presents the case of a 73-year-old female patient referred to our hospital for uncontrolled asthma for 35 years. The diagnosis of ABPA was made on the basis of clinical symptoms, peripheral blood eosinophilia, elevated total serum immunoglobulin E, positive aspergillus serology, and bronchiectasis with mucoid impaction. Systemic corticosteroids and antifungal therapy came up with satisfactory clinical results.

摘要

变应性支气管肺曲霉病(ABPA)是哮喘和囊性纤维化患者中一种诊断不足的肺部疾病。其临床和诊断表现源于对寄生于支气管黏液中的曲霉菌所表达的多种抗原的过敏反应。本报告介绍了一名73岁女性患者的病例,该患者因35年未得到控制的哮喘转诊至我院。根据临床症状、外周血嗜酸性粒细胞增多、血清总免疫球蛋白E升高、曲霉血清学阳性以及伴有黏液嵌塞的支气管扩张做出了ABPA的诊断。全身用皮质类固醇和抗真菌治疗取得了满意的临床效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f52/10250130/e06c8156b40e/cureus-0015-00000038778-i01.jpg

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