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一名患有变应性支气管肺曲霉病的48岁男性:一例罕见病例报告。

A 48-year-old male with allergic bronchopulmonary aspergillosis: a rare case report.

作者信息

Khattab Khalid, Alhomsi Khaled, Othman Abdulrahman Ahmad, Alfandi Abdullah, Almohammad Taha, Al-Kubati Anas Saeed Abdulmalek, Alkateb Sereen Fahed, Alboatani Mohamad Yazan, Darouich Ayham, Sleiay Bilal, Sleiay Mouhammed

机构信息

Al-Mouwasat University Hospital, Damascus,Syria.

Education Quality and Scientific Research Council, Al-Sham Private University, Damascus, Syria.

出版信息

Ann Med Surg (Lond). 2025 Mar 27;87(4):2398-2401. doi: 10.1097/MS9.0000000000003087. eCollection 2025 Apr.

DOI:10.1097/MS9.0000000000003087
PMID:40212161
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11981463/
Abstract

INTRODUCTION

Allergic bronchopulmonary mycoses, primarily from , complicate asthma and cystic fibrosis, presenting diagnostic challenges due to overlapping respiratory symptoms.

CASE PRESENTATION

A 48-year-old male with asthma and a history of Guillain-Barré syndrome presented with cough, chest pain, dyspnea, and weight loss. He was diagnosed with allergic bronchopulmonary aspergillosis after a series of investigations, including CT scans and bronchoscopy.

CLINICAL DISCUSSION

Allergic bronchopulmonary aspergillosis (ABPA) is a rare lung disease caused by an immune reaction to in individuals with pre-existing respiratory conditions like asthma or cystic fibrosis. The primary treatment for ABPA involves systemic corticosteroids, often combined with antifungal agents, to reduce the need for long-term high-dose steroid therapy.

CONCLUSION

This case highlights the need for accurate and early diagnosis of ABPA, especially in patients with asthma or other respiratory diseases, which helps prevent potential complications. Additionally, the case provides valuable insights into how to manage patients with ABPA, contributing to the improvement of protocols and medical care in the future.

摘要

引言

变应性支气管肺真菌病主要由……引起,使哮喘和囊性纤维化复杂化,由于呼吸道症状重叠而带来诊断挑战。

病例介绍

一名48岁男性,患有哮喘且有格林-巴利综合征病史,出现咳嗽、胸痛、呼吸困难和体重减轻症状。经过一系列检查,包括CT扫描和支气管镜检查,他被诊断为变应性支气管肺曲霉菌病。

临床讨论

变应性支气管肺曲霉菌病(ABPA)是一种罕见的肺部疾病,由对曲霉菌的免疫反应引起,发生于患有哮喘或囊性纤维化等既往呼吸道疾病的个体。ABPA的主要治疗方法包括全身使用糖皮质激素,通常联合抗真菌药物,以减少长期高剂量激素治疗的需求。

结论

该病例强调了对ABPA进行准确早期诊断的必要性,尤其是在哮喘或其他呼吸道疾病患者中,这有助于预防潜在并发症。此外,该病例为如何管理ABPA患者提供了有价值的见解,有助于未来改进治疗方案和医疗护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/146c/11981463/e8e744ace975/ms9-87-2398-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/146c/11981463/5eb8f4e2bedf/ms9-87-2398-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/146c/11981463/e8e744ace975/ms9-87-2398-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/146c/11981463/5eb8f4e2bedf/ms9-87-2398-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/146c/11981463/e8e744ace975/ms9-87-2398-g002.jpg

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