Elmekresh Amr, Al Shaikh Yazan, Alhayek Rafe, Saeedi Yaser
Department of Urology, Dubai Health Authority, Dubai Hospital, Dubai, United Arab Emirates.
Urol Ann. 2023 Apr-Jun;15(2):232-234. doi: 10.4103/ua.ua_117_22. Epub 2023 Feb 14.
Intravesical Calmette-Guérin (BCG) therapy for nonmuscle-invasive bladder cancer rarely leads to the development of granulomatous renal masses (renal BCGosis). The management includes nephroureterectomy, antitubercular therapy (ATT), or both. Here, we present a case of a 62-year-old male who was treated with ATT alone for renal masses. Six months after intravesical BCG therapy for transitional cell carcinoma, he developed high-grade fever and night sweat and had multiple renal parenchymal hypodensities on computed tomography (CT) scan. Repeat CT scan 6 months after ATT revealed full resolution of renal hypodensities. This case report highlights the importance of follow-up for early detection of adverse effects of BCG treatment.
膀胱内灌注卡介苗(BCG)治疗非肌层浸润性膀胱癌很少导致肉芽肿性肾肿块(肾卡介苗病)的发生。治疗方法包括肾输尿管切除术、抗结核治疗(ATT)或两者兼用。在此,我们报告一例62岁男性,其肾肿块仅接受了ATT治疗。在因移行细胞癌接受膀胱内BCG治疗6个月后,他出现高热和盗汗,计算机断层扫描(CT)显示多个肾实质低密度影。ATT治疗6个月后复查CT显示肾低密度影完全消失。本病例报告强调了随访对于早期发现BCG治疗不良反应的重要性。