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一种具有增强电化学稳定性的基于二氧化硅杂化酶的生物传感器,用于精确检测葡萄糖。

A SiO Hybrid Enzyme-Based Biosensor with Enhanced Electrochemical Stability for Accuracy Detection of Glucose.

作者信息

Mei Li, Yang Yiting, Li Jiagen, Shang Shuyong, Fu Xiaohong

机构信息

Department of Culinary, Sichuan Tourism University, Chengdu 610100, China.

Provincial Key Laboratory for Structural Optimization and Application of Functional Molecules, Chengdu Normal University, Chengdu 611130, China.

出版信息

Int J Anal Chem. 2023 Jun 2;2023:6620613. doi: 10.1155/2023/6620613. eCollection 2023.

Abstract

A novel enzyme-based biosensor for glucose detection is successfully developed using layer-by-layer assembly technology. The introduction of commercially available SiO was found to be a facile way to improve overall electrochemical stability. After 30 CV cycles, the proposed biosensor could retain 95% of its original current. The biosensor presents good detection stability and reproducibility with the detection concentration range of 1.96 × 10 to 7.24 × 10 M. This study demonstrated that the hybridization of cheap inorganic nanoparticles was a useful method in preparing high-performance biosensors with a much lower cost.

摘要

一种基于酶的新型葡萄糖检测生物传感器利用层层组装技术成功研发。研究发现引入市售的二氧化硅是提高整体电化学稳定性的简便方法。经过30次循环伏安(CV)测试后,所提出的生物传感器可保留其原始电流的95%。该生物传感器在1.96×10至7.24×10 M的检测浓度范围内呈现出良好的检测稳定性和重现性。本研究表明,廉价无机纳米颗粒的杂化是一种以低得多的成本制备高性能生物传感器的有用方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c1/10256442/e1729ef90ef3/IJAC2023-6620613.001.jpg

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