Kovacik Carrie N, Shah Megan D, Thomas Tania A, Eby Joshua C
Department of Pharmacy, University of Virginia Health, Charlottesville, Virginia, USA.
Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health, Charlottesville, Virginia, USA.
Open Forum Infect Dis. 2023 May 3;10(6):ofad239. doi: 10.1093/ofid/ofad239. eCollection 2023 Jun.
After receiving a monitored first-dose antimicrobial infusion at an infusion center, 6 of 93 (6%) patients enrolled in outpatient parenteral antimicrobial therapy services experienced an immediate reaction, none of which were consistent with immunoglobulin E-mediated reactions. These findings suggest it would be reasonable to forgo monitoring for most patients receiving first-dose intravenous antimicrobials outpatient.
在输液中心接受首剂抗菌药物监测输液后,93名参加门诊胃肠外抗菌治疗服务的患者中有6名(6%)出现即刻反应,均与免疫球蛋白E介导的反应不符。这些发现表明,对于大多数门诊接受首剂静脉抗菌药物治疗的患者而言,放弃监测是合理的。