[来自北极假单胞菌526的谷氨酰胺（天冬酰胺）酶的生物学特性]
[Biological properties of glutamin-(asparagin-)ase from Pseudomonas boreopolis 526].
作者信息
Pekhov A A, Zanin V A, Kozlov A M, Iurchenko A Ia, Kondrat'eva N A
出版信息
Biull Eksp Biol Med. 1986 Jul;102(7):71-4.
PMID:3730598
Abstract
Glutamine(asparagine)ase from Ps. boreopolis 526 has an antineoplastic effect on lymphoid leukemia P-388. The enzyme half-life in the mouse serum is 8.5 hours. Glutamine(asparagine)ase has no cross-antigenicity with L-asparaginase from E. coli (Bayer, FRG). Specific antibodies against L-asparaginase (Bayer, FRG) do not influence the activity of glutamine(asparagine)ase.
摘要
来自博雷奥波利斯假单胞菌526的谷氨酰胺（天冬酰胺）酶对淋巴细胞白血病P - 388具有抗肿瘤作用。该酶在小鼠血清中的半衰期为8.5小时。谷氨酰胺（天冬酰胺）酶与来自大肠杆菌（德国拜耳公司）的L - 天冬酰胺酶没有交叉抗原性。针对L - 天冬酰胺酶（德国拜耳公司）的特异性抗体不影响谷氨酰胺（天冬酰胺）酶的活性。
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