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血脂异常。

Dyslipidemia.

机构信息

Johns Hopkins University School of Medicine, Baltimore, Maryland (M.A., C.J.L.).

出版信息

Ann Intern Med. 2023 Jun;176(6):ITC81-ITC96. doi: 10.7326/AITC202306200. Epub 2023 Jun 13.

Abstract

Dyslipidemia is an important risk factor for coronary artery disease and stroke. All persons with dyslipidemia should be advised to focus on lifestyle interventions, including regular aerobic exercise, a healthy diet, maintenance of a healthy weight, and abstinence from smoking. In addition to lifestyle interventions, lipid-lowering therapy should be considered for persons at moderate to high risk for atherosclerotic cardiovascular disease based on validated risk equations. Statin therapy is the first-line medical treatment for dyslipidemia due to its effectiveness and favorable adverse effect profile, but newer treatments provide additional tools for clinicians to effectively treat dyslipidemia.

摘要

血脂异常是冠心病和脑卒中的重要危险因素。所有血脂异常患者均应建议其注重生活方式干预,包括定期进行有氧运动、健康饮食、保持健康体重和戒烟。除生活方式干预外,还应根据经过验证的风险方程,考虑对存在动脉粥样硬化性心血管疾病中高危风险的患者进行降脂治疗。他汀类药物治疗由于其有效性和良好的不良反应谱,是血脂异常的一线治疗药物,但新型治疗方法为临床医生有效治疗血脂异常提供了更多手段。

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