Department of Otorhinolaryngology, Head and Neck Surgery, Aarhus University Hospital, Aarhus, Denmark.
Unit of Clinical Biostatistics, Aalborg University Hospital, Aalborg, Denmark.
Sleep Med. 2023 Aug;108:16-21. doi: 10.1016/j.sleep.2023.05.011. Epub 2023 May 30.
In this nationwide study, we used Danish population registries to estimate the excess risk of receiving permanent social security benefits for patients with obstructive sleep apnea (OSA) and to track their labour force participation.
We identified all Danish citizens receiving a diagnosis of OSA between 1995 and 2015. As a reference cohort, we randomly selected 10 citizens for each patient, matched by sex and birth year. Using the Fine and Gray competing risk regression, we estimated the cumulative incidences of receiving permanent social security benefits. Cox proportional hazard models were used to compare the risk of receiving permanent social security benefits in patients with OSA compared to the reference cohort. The Danish Rational Economic Agents' Model (DREAM) database was used to identify the labour market status prior to diagnosis, at time of diagnosis, and after diagnosis.
We identified 48,168 patients with OSA. A total of 12,413 (25.8%) patients with OSA had received permanent social security benefits, compared with 75,812 (15.7%) individuals in the reference cohort. Patients with OSA had a significantly increased risk of receiving permanent social security benefits when compared with the reference cohort (hazard ratio, 1.95; 95% CI, 1.88-2.02; and subhazard ratio, 1.92; 95% CI, 1.85-1.98). Work participation was lower for OSA patients compared to references at all time-points.
Patients with OSA have a moderately increased risk of receiving permanent social security benefits in Denmark after controlling for available confounders.
在这项全国性研究中,我们利用丹麦人口登记系统来估计阻塞性睡眠呼吸暂停(OSA)患者获得永久性社会保障福利的超额风险,并追踪他们的劳动力参与情况。
我们确定了 1995 年至 2015 年期间所有被诊断为 OSA 的丹麦公民。作为参考队列,我们为每位患者随机选择了 10 名性别和出生年份匹配的公民。使用 Fine 和 Gray 竞争风险回归,我们估计了获得永久性社会保障福利的累积发生率。使用 Cox 比例风险模型比较了 OSA 患者与参考队列获得永久性社会保障福利的风险。使用丹麦理性经济代理人模型(DREAM)数据库来识别诊断前、诊断时和诊断后的劳动力市场状况。
我们确定了 48168 例 OSA 患者。共有 12413 例(25.8%)OSA 患者获得了永久性社会保障福利,而参考队列中有 75812 例(15.7%)。与参考队列相比,OSA 患者获得永久性社会保障福利的风险显著增加(风险比,1.95;95%置信区间,1.88-2.02;和亚风险比,1.92;95%置信区间,1.85-1.98)。与参考组相比,OSA 患者在所有时间点的工作参与率都较低。
在控制了可用混杂因素后,丹麦 OSA 患者获得永久性社会保障福利的风险适度增加。