Yamasaki D S, Krauthamer G M, Rhoades R W
Brain Res. 1986 Jul 23;378(2):223-33. doi: 10.1016/0006-8993(86)90925-x.
The superior collicular (SC) cells which project to the intralaminar thalamus (IT; nuclei centralis lateralis, CL; paracentralis, PC; parafascicularis, Pf) in the rat were identified by means of retrograde transport of wheatgerm agglutinin conjugated horseradish peroxidase (WGA-HRP). SC-IT cells were located throughout the mediolateral and rostrocaudal extents of the tectum ipsilateral to the thalamic injection. In this SC, they had a primarily bilaminar distribution in the lower one-half of the stratum griseum intermediale (SGI) and upper portion of the stratum griseum profundum (SGP). In these laminae, SC-IT cells were arranged in clusters or patches similar to those which have been described for many inputs to the deep SC laminae. A small number of SC-IT cells were also observed in the deep laminae of the tectum contralateral to the thalamic injection. Double labelling experiments using True Blue (TB) and Diamidino Yellow (DY) demonstrated that less than 1% of the contralaterally projecting SC-IT cells also innervated ipsilateral IT. Anterograde tracing with [3H]leucine demonstrated further that SC projected heavily to CL, PC and Pf. This projection also extended into the medial portion of the posterior thalamus (PO).
通过结合辣根过氧化物酶的小麦胚凝集素（WGA-HRP）逆行运输法，鉴定了大鼠中投射至丘脑板内核（IT；外侧中央核，CL；中央旁核，PC；束旁核，Pf）的上丘（SC）细胞。丘脑注射同侧的顶盖中，SC-IT细胞分布于顶盖的整个内外侧和前后范围。在这个上丘中，它们主要呈双分层分布于中间灰质层（SGI）下半部分和深层灰质层（SGP）上半部分。在这些层中，SC-IT细胞聚集成簇或斑块，类似于已描述的许多投射至深层上丘层的输入。在丘脑注射对侧的顶盖深层中也观察到少量的SC-IT细胞。使用真蓝（TB）和双脒基黄（DY）的双重标记实验表明，不到1%的对侧投射SC-IT细胞也支配同侧的IT。用[3H]亮氨酸进行的顺行追踪进一步表明，SC大量投射至CL、PC和Pf。该投射也延伸至丘脑后部（PO）的内侧部分。
