上颌窦鳞状细胞癌患者的第二原发性癌
Second primary carcinomas in patients with squamous cell carcinoma of the maxillary sinus.
作者信息
Shibuya H, Amagasa T, Hanai A, Horiuchi J, Suzuki S
出版信息
Cancer. 1986 Sep 1;58(5):1122-5. doi: 10.1002/1097-0142(19860901)58:5<1122::aid-cncr2820580524>3.0.co;2-4.
Three hundred fifty-one patients with squamous cell carcinoma of the maxillary sinus received radiation therapy between 1953 and 1984. Nine subsequently developed cancers in other organs than the maxillary sinus, and five squamous cell carcinomas occurred in the second maxillary sinus. Analysis by the person-year approach suggested a remarkably increased risk of 67 times for second sinus cancer and no additional increased risk of cancers to other organs, such as the upper aerodigestive tract.
1953年至1984年间，351例上颌窦鳞状细胞癌患者接受了放射治疗。其中9例随后在除上颌窦以外的其他器官发生癌症，5例在对侧上颌窦发生鳞状细胞癌。采用人年法分析表明，对侧鼻窦癌的风险显著增加67倍，而上呼吸道等其他器官的癌症风险没有额外增加。
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