Division of Cardiac Surgery, Department of Surgery, Thomas Jefferson University, 1025 Walnut St, Suite 607, Philadelphia, PA, 19107, USA.
Gen Thorac Cardiovasc Surg. 2023 Dec;71(12):723-729. doi: 10.1007/s11748-023-01943-6. Epub 2023 Jun 13.
Although an ultrasonic harmonic scalpel (HS) has been used to harvest the internal mammary artery (IMA) for coronary artery bypass grafting, the benefits and risks compared to conventional electrocautery (EC) are not clear. We aimed to compare the outcomes of HS versus EC for IMA harvesting.
An electronic search was performed to identify all relevant studies. Baseline characteristics, perioperative variables, and clinical outcomes were extracted and pooled for meta-analysis.
This meta-analysis included 12 studies. Pooled analyses demonstrated that both groups had comparable preoperative baseline characteristics including age, gender, and left ventricular ejection fraction. HS included more diabetic patients [33% (95% CI 30, 35) vs. 27% (23, 31), p = 0.01]. Harvest time for unilateral IMA was significantly longer with HS than EC [39 (31, 47) minutes vs. 25 (17, 33) minutes, p < 0.01]. However, the rate of pedicled unilateral IMA was significantly higher for EC compared with HS [20% (17, 24) vs. 8% (7, 9), p < 0.01]. The rate of intact endothelium was significantly higher with HS than EC [95% (88, 98) vs. 81% (68, 89), p < 0.01). There was no significant difference in postoperative outcomes including bleeding [3% (2, 4)], sternal infection [3% (2, 4)], and operative/30-day mortality [3% (2, 4)].
HS required longer IMA harvest times which could be partially attributed to a higher skeletonization rate in this category. HS may cause less endothelial injury than EC; however, no significant differences in postoperative outcomes were seen between the groups.
尽管超声谐波刀(HS)已被用于采集内乳动脉(IMA)进行冠状动脉旁路移植术,但与传统电刀(EC)相比,其益处和风险尚不清楚。我们旨在比较 HS 与 EC 用于 IMA 采集的结果。
进行电子检索以确定所有相关研究。提取并汇总基线特征、围手术期变量和临床结果进行荟萃分析。
本荟萃分析包括 12 项研究。汇总分析表明,两组患者的术前基线特征具有可比性,包括年龄、性别和左心室射血分数。HS 组中糖尿病患者比例更高[33%(95%CI 30,35)比 27%(23,31),p=0.01]。单侧 IMA 的 HS 采集时间明显长于 EC [39(31,47)分钟比 25(17,33)分钟,p<0.01]。然而,EC 组中带蒂单侧 IMA 的比例明显高于 HS 组[20%(17,24)比 8%(7,9),p<0.01]。HS 组中完整内皮的比例明显高于 EC 组[95%(88,98)比 81%(68,89),p<0.01]。术后结果无显著差异,包括出血[3%(2,4)]、胸骨感染[3%(2,4)]和手术/30 天死亡率[3%(2,4)]。
HS 需要更长的 IMA 采集时间,这可能部分归因于此类患者的骨骼化率较高。HS 可能比 EC 引起的内皮损伤更小;然而,两组间术后结果无显著差异。