Zhang Xiaoying, Liu Simin, Liu Ying, Lv Zhongwei, Yang Jianshe
Department of Nuclear Medicine, Shanghai Tenth People's Hospital of Nanjing Medical University, Shanghai 200072, China.
Department of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
Curr Med Imaging. 2023 Jun 1. doi: 10.2174/1573405620666230601111844.
Background Monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL) is a rare, rapidly progressive, primary intestinal T-cell lymphoma. The most common site of occurrence is on the small intestine. The prognosis of MEITL is extremely poor due to delayed diagnosis and lack of targeted therapy. Case Summary A case of MEITL involving the entire small bowel, part of the colon, rectum, mesenteric lymph nodes, and liver is herein reported. We are presenting the 18F-FDG PET/CT features of MEITL, which showed all involved lesions with increased FDG activity. The MRI and pathological characteristics of MEITL were also described. Furthermore, some malignant diseases and benign diseases should be considered in the differential diagnosis. Conclusion Based on the lesions with a high accumulation of FDG, our case shows the involved extent of MEITL, which is helpful for biopsy and treatment option decisions. We expect more could know about this disease and make an early diagnosis to improve the outcomes of MEITL.
背景 单形性上皮样肠道T细胞淋巴瘤（MEITL）是一种罕见的、进展迅速的原发性肠道T细胞淋巴瘤。最常见的发生部位是小肠。由于诊断延迟和缺乏靶向治疗，MEITL的预后极差。病例总结 本文报告1例累及全小肠、部分结肠、直肠、肠系膜淋巴结及肝脏的MEITL。我们展示了MEITL的18F-FDG PET/CT特征，显示所有受累病变的FDG活性增加。还描述了MEITL的MRI及病理特征。此外，鉴别诊断时应考虑一些恶性疾病和良性疾病。结论 基于FDG高度积聚的病变，我们的病例显示了MEITL的受累范围，这有助于活检及治疗方案的决策。我们期望更多人了解这种疾病并进行早期诊断，以改善MEITL的治疗效果。
