Bożek Andrzej, Kozłowska Renata, Sybila Paweł, Miodońska Martyna, Mędrala Agata, Foks-Ciekalska Aleksandra, Ignasiak Beata
Clinical Department of Internal Medicine, Dermatology and Allergology in Zabrze, Medical University of Silesia in Katowice, Poland.
Allergy Outpatient Clinic, Świętochłowice, Poland.
Postepy Dermatol Alergol. 2023 Apr;40(2):321-325. doi: 10.5114/ada.2022.124313. Epub 2023 Jan 19.
Local allergic rhinitis (LAR) is one of the endotypes of rhinitis which occurs commonly in different age groups.
To present the occurrence and characteristics of LAR in Polish children and adolescents.
In the study protocol, three hundred sixty-one patients aged 5-17 with chronic rhinitis were included from 8 centres in Poland. Medical history and diagnostic procedures were performed with aeroallergens: skin prick tests, allergen-specific serum IgE and nasal provocation tests. In addition to LAR, allergic rhinitis (AR), dual allergic rhinitis (DUAL) and non-allergic rhinitis (NAR) were explored and compared.
LAR was confirmed in 21% of patients, systemic allergic rhinitis (SAR) in 43.9%, DUAL in 9.4% and NAR in 33.9% of patients. Based on nasal provocation test (NPT), allergy to HDM prevailed in the LAR group (68%), grass in the SAR group (58%), and grass and HDM in the DUAL group (32% and 64%). Girls were prevalent in the LAR group, and severe rhinitis and asthma were more common than other endotypes ( < 0.05).
LAR is a common disease in children and adolescents and is often associated with severe rhinitis and frequently coexists with asthma.
局部过敏性鼻炎（LAR）是鼻炎的一种内型，常见于不同年龄组。
介绍波兰儿童和青少年中LAR的发生情况及特征。
在该研究方案中，从波兰的8个中心纳入了361名年龄在5至17岁的慢性鼻炎患者。采用空气变应原进行病史采集和诊断程序：皮肤点刺试验、变应原特异性血清IgE和鼻激发试验。除了LAR，还对过敏性鼻炎（AR）、双重过敏性鼻炎（DUAL）和非过敏性鼻炎（NAR）进行了探究和比较。
21%的患者确诊为LAR，43.9%为全身性过敏性鼻炎（SAR），9.4%为DUAL，33.9%为NAR。基于鼻激发试验（NPT），LAR组中对屋尘螨过敏占主导（68%），SAR组中对草过敏占主导（58%），DUAL组中对草和屋尘螨过敏分别占32%和64%。LAR组中女孩居多，且重度鼻炎和哮喘比其他内型更为常见（P<0.05）。
LAR在儿童和青少年中是一种常见疾病，常与重度鼻炎相关，且常与哮喘并存。
