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慢性酒精使用相关脑病,其表现与正常压力脑积水几乎相同。

Chronic Alcohol Use Associated Encephalopathy With a Nearly Identical Presentation to Normal Pressure Hydrocephalus.

作者信息

Patel Shreya, Malhotra Vasu, Scwartz Shani, Smith Travis, Malhotra Vikas

机构信息

Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, USA.

Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Clearwater, USA.

出版信息

Cureus. 2023 May 13;15(5):e38977. doi: 10.7759/cureus.38977. eCollection 2023 May.

Abstract

We present the case of a 52-year-old male who arrived at the Emergency Department after several ground-level falls in the past month. He complained of urinary incontinence, mild confusion, headaches, and appetite loss in the past month as well. Brain computed tomography (CT) and magnetic resonance imaging (MRI) were performed, which showed enlarged ventricles with moderately prominent cortical atrophy and no acute abnormalities. It was decided to conduct a cisternogram study with serial scans. The study showed a type IIIa cerebrospinal fluid (CSF) flow pattern at 24 hours. At the 48- and 72-hour marks, the study displayed an absence of radiotracer activity within the ventricles, while all the activity was concentrated within the cerebral cortices. These findings successfully ruled out normal pressure hydrocephalus (NPH) due to the highly specific indication of normal CSF circulation pattern. The patient was treated with thiamine and advised to quit drinking, as well as return for follow-up in one month as an outpatient for a repeat brain CT.

摘要

我们报告一例52岁男性病例,该患者在过去一个月内多次平地摔倒后前来急诊科就诊。他还主诉在过去一个月出现尿失禁、轻度意识模糊、头痛及食欲减退。进行了脑部计算机断层扫描(CT)和磁共振成像(MRI),结果显示脑室扩大,伴有中度明显的皮质萎缩,无急性异常。决定进行连续扫描的脑池造影研究。该研究显示24小时时脑脊液(CSF)呈IIIa型流动模式。在48小时和72小时标记时,研究显示脑室内无放射性示踪剂活性,而所有活性均集中在大脑皮质内。由于脑脊液循环模式正常这一高度特异性表现,这些发现成功排除了正常压力脑积水(NPH)。患者接受了硫胺素治疗,并被建议戒酒,同时作为门诊患者在一个月后复诊进行重复脑部CT检查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d9a/10259879/02b27cc22026/cureus-0015-00000038977-i01.jpg

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