Chi Feng, Zhou Shenkang, Bi Tienan, Zhao Wenjun, Wang Xiang
Department of Gastrointestinal Surgery, Taizhou Hospital of Zhejiang Province, Zhejiang University, Linhai, China.
Department of Vascular Surgery, Taizhou Hospital of Zhejiang Province, Zhejiang University, Linhai, China.
Arch Med Sci. 2021 Mar 25;19(3):633-637. doi: 10.5114/aoms/112531. eCollection 2023.
A dilated inferior mesenteric vein has been reported in rectal cancer patients. However, no study has yet reported inferior mesenteric artery (IMA) enlargement in rectal cancer. We aimed to assess the relationship between the IMA diameter and rectal cancer.
Patients diagnosed with rectal cancer and a control group of 42 patients in our hospital from July 2017 to June 2019 were evaluated. The IMA diameter was independently measured by two observers on axial computed tomography images.
The mean IMA diameter was wider in rectal cancer patients (2.49 ±0.53 mm) than in the control group (2.20 ±0.47 mm, < 0.001). The IMA diameter of patients with stage I, stage II, stage III, and stage IV cancers was 2.24 ±0.36 mm, 2.45 ±0.39 mm, 2.80 ±0.55 mm, and 2.85 ±0.51 mm, respectively ( < 0.001). The IMA diameter correlated positively and moderately with TNM stage ( = 0.519, < 0.001). The IMA diameter of patients with T1, T2, T3, and T4 tumors was 2.18 ±0.31 mm, 2.39 ±0.50 mm, 2.55 ±0.48 mm, and 2.73 ±0.51 mm, respectively ( < 0.001). The IMA diameter also correlated positively and moderately with T stage ( = 0.457, < 0.001). The IMA diameter of patients with N0, N1, and N2 tumors was 2.37 ±0.39 mm, 2.83 ±0.60 mm, and 2.71 ±0.40 mm, respectively ( < 0.001); however, the IMA diameter did not correlate with N stage ( = 0.166, = 0.077). Patients with M1 tumors had a wider IMA diameter than patients with M0 tumors ( = 0.011).
The IMA in rectal cancer patients enlarges as the TNM stage gets higher. The IMA diameter can be accepted as a possibly important marker for the staging of rectal cancer.
已有报道称直肠癌患者肠系膜下静脉扩张。然而，尚无研究报道直肠癌患者肠系膜下动脉（IMA）增粗的情况。我们旨在评估IMA直径与直肠癌之间的关系。
对2017年7月至2019年6月在我院诊断为直肠癌的患者及42名对照组患者进行评估。由两名观察者在轴向计算机断层扫描图像上独立测量IMA直径。
直肠癌患者的平均IMA直径（2.49±0.53mm）比对照组（2.20±0.47mm，<0.001）更宽。I期、II期、III期和IV期癌症患者的IMA直径分别为2.24±0.36mm、2.45±0.39mm、2.80±0.55mm和2.85±0.51mm（<0.001）。IMA直径与TNM分期呈正相关且为中度相关（=0.519，<0.001）。T1、T2、T3和T4肿瘤患者的IMA直径分别为2.18±0.31mm、2.39±0.50mm、2.55±0.48mm和2.73±0.51mm（<0.001）。IMA直径与T分期也呈正相关且为中度相关（=0.457，<0.001）。N0、N1和N2肿瘤患者的IMA直径分别为2.37±0.39mm、2.83±0.60mm和2.71±0.40mm（<0.001）；然而，IMA直径与N分期无相关性（=0.166，=0.077）。M1肿瘤患者的IMA直径比M0肿瘤患者更宽（=0.011）。
直肠癌患者的IMA随着TNM分期升高而增粗。IMA直径可被视为直肠癌分期的一个可能重要的标志物。
