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III期和IV期卵巢子宫内膜异位囊肿患者的特征及术后抗苗勒管激素变化趋势

Characteristics of patients with stage III and IV ovarian endometriomas and trends in postoperative anti-Mullerian hormone changes.

作者信息

Gao Kefei, Lian Wenqin, Zhao Rui, Xiong Jian

机构信息

Department of Obstetrics and Gynaecology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.

Department of Burns and Plastic and Wound Repair Surgery, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.

出版信息

Arch Med Sci. 2023 May 24;19(3):800-804. doi: 10.5114/aoms/162114. eCollection 2023.

DOI:10.5114/aoms/162114
PMID:37313209
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10259385/
Abstract

INTRODUCTION

This study aimed to investigate the manifestations of postoperative Anti-Mullerian hormone (AMH) changes in patients with stage III and IV ovarian endometriomas.

METHODS

Trends in postoperative AMH were categorized and described, and the risk factors for postoperative AMH decline were screened using dichotomous logistic regression.

RESULTS

The overall trend of postoperative AMH decreased, with a more significant decrease in stage IV than stage III cases. Elevated preoperative CA-125 levels, a history of caesarean section, and abortion were independent risk factors for postoperative AMH decline.

CONCLUSIONS

There is a general trend toward decreasing AMH levels after surgery, but each case may also show a different elevation.

摘要

引言

本研究旨在调查Ⅲ期和Ⅳ期卵巢子宫内膜异位症患者术后抗苗勒管激素（AMH）变化的表现。

方法

对术后AMH的变化趋势进行分类和描述，并采用二分类逻辑回归筛选术后AMH下降的危险因素。

结果

术后AMH总体呈下降趋势，Ⅳ期病例下降幅度比Ⅲ期更显著。术前CA-125水平升高、剖宫产史和流产史是术后AMH下降的独立危险因素。

结论

术后AMH水平总体呈下降趋势，但每个病例也可能呈现不同的升高情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5f3/10259385/9e5e64c19cf6/AMS-19-3-162114-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5f3/10259385/9e5e64c19cf6/AMS-19-3-162114-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5f3/10259385/9e5e64c19cf6/AMS-19-3-162114-g001.jpg

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本文引用的文献

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Endometriosis is a chronic systemic disease: clinical challenges and novel innovations.子宫内膜异位症是一种慢性全身性疾病：临床挑战与新的创新。
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Anti-Müllerian Hormone and Ovarian Reserve: Update on Assessing Ovarian Function.抗苗勒管激素与卵巢储备：评估卵巢功能的最新进展。
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Factors associated with deep infiltrating endometriosis versus ovarian endometrioma in China: a subgroup analysis from the FEELING study.中国深部浸润性子宫内膜异位症与卵巢子宫内膜异位囊肿相关因素的研究：FEELING 研究的亚组分析。
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Effect of surgery on ovarian reserve in women with endometriomas, endometriosis and controls.手术对患有子宫内膜异位囊肿、子宫内膜异位症的女性及对照组女性卵巢储备功能的影响。
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